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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUOX1 All Species: 22.73
Human Site: Y834 Identified Species: 45.45
UniProt: Q9NRD9 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRD9 NP_787954.1 1551 177235 Y834 A D K D G N G Y L S F R E F L
Chimpanzee Pan troglodytes XP_001163196 1551 177072 Y834 A D K D G N G Y L S F R E F L
Rhesus Macaque Macaca mulatta XP_001111340 1551 176921 Y834 A D K D G N G Y L S F R E F L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus NP_001092767 1551 177113 Y834 A D K D G N G Y L S F R E F L
Rat Rattus norvegicus Q8CIY2 1551 177179 Y834 A D K D G N G Y L S F R E F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518643 1547 175433 K833 S M F S L A D K D G N G Y I S
Chicken Gallus gallus XP_425053 1523 173782 S801 V N S M F V D S M F S L A D K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919394 1322 150039 A630 E P A H G T T A S E W L G H N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQH2 1475 170768 R760 F G L R P G E R R R R S D A S
Honey Bee Apis mellifera XP_624355 1492 172466 S779 P G E R R R R S E D S D S G E
Nematode Worm Caenorhab. elegans O61213 1497 170397 A779 F R E A Y A K A F N D S E L Q
Sea Urchin Strong. purpuratus NP_001118237 1671 189876 S958 V D Q D N S G S I S F R E F L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 96.7 N.A. N.A. 91 90.1 N.A. 73.9 65.1 N.A. 47.1 N.A. 39.9 40.3 34.3 41.6
Protein Similarity: 100 99.4 97.8 N.A. N.A. 95 94.4 N.A. 84.4 78.4 N.A. 61.7 N.A. 58 60.2 55.9 59.3
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. 0 0 N.A. 6.6 N.A. 0 0 6.6 60
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 6.6 13.3 N.A. 13.3 N.A. 6.6 6.6 20 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 42 0 9 9 0 17 0 17 0 0 0 0 9 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 50 0 50 0 0 17 0 9 9 9 9 9 9 0 % D
% Glu: 9 0 17 0 0 0 9 0 9 9 0 0 59 0 9 % E
% Phe: 17 0 9 0 9 0 0 0 9 9 50 0 0 50 0 % F
% Gly: 0 17 0 0 50 9 50 0 0 9 0 9 9 9 0 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 0 0 0 9 0 % I
% Lys: 0 0 42 0 0 0 9 9 0 0 0 0 0 0 9 % K
% Leu: 0 0 9 0 9 0 0 0 42 0 0 17 0 9 50 % L
% Met: 0 9 0 9 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 9 42 0 0 0 9 9 0 0 0 9 % N
% Pro: 9 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 0 9 0 17 9 9 9 9 9 9 9 50 0 0 0 % R
% Ser: 9 0 9 9 0 9 0 25 9 50 17 17 9 0 17 % S
% Thr: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % T
% Val: 17 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 42 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _