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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTPS2
All Species:
38.48
Human Site:
Y292
Identified Species:
65.13
UniProt:
Q9NRF8
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRF8
NP_001137474.1
586
65678
Y292
W
R
N
M
A
D
R
Y
E
R
L
Q
K
I
C
Chimpanzee
Pan troglodytes
XP_520953
586
65363
Y292
K
K
K
R
E
I
K
Y
E
R
L
Q
K
I
C
Rhesus Macaque
Macaca mulatta
XP_001117012
616
69695
Y322
W
R
N
M
A
D
R
Y
E
R
L
Q
K
I
C
Dog
Lupus familis
XP_537968
586
65447
Y292
W
R
N
M
A
D
R
Y
E
R
L
Q
K
M
C
Cat
Felis silvestris
Mouse
Mus musculus
P70303
586
65496
Y292
W
K
A
M
A
D
R
Y
E
R
L
Q
K
I
C
Rat
Rattus norvegicus
Q5U2N0
586
65655
Y292
W
K
T
M
A
D
R
Y
E
R
L
Q
K
I
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515783
691
77183
Y292
W
K
A
M
A
D
R
Y
E
R
L
Q
K
S
C
Chicken
Gallus gallus
Q5F3Z1
586
66050
Y292
W
K
K
M
A
D
R
Y
E
R
L
L
K
V
C
Frog
Xenopus laevis
Q6GME1
578
65100
Y292
W
K
R
M
A
D
R
Y
E
R
L
L
K
T
C
Zebra Danio
Brachydanio rerio
Q6PEI7
591
66577
S292
W
K
E
M
S
D
R
S
D
R
L
L
E
Q
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUL1
627
69429
T292
W
R
D
L
A
R
R
T
E
T
V
R
R
E
V
Honey Bee
Apis mellifera
XP_624223
604
67926
I293
W
R
D
L
A
D
R
I
D
H
L
R
K
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P28274
579
64692
F297
W
K
A
T
T
G
N
F
D
E
S
M
E
T
V
Red Bread Mold
Neurospora crassa
Q7RZV2
568
63157
P284
A
K
W
Q
K
I
V
P
L
G
Y
A
E
T
V
Conservation
Percent
Protein Identity:
100
92.8
88.1
96.2
N.A.
90.4
90.6
N.A.
75.5
85.4
79.8
75.6
N.A.
61
63
N.A.
N.A.
Protein Similarity:
100
94.5
89.7
97.9
N.A.
95
94.7
N.A.
78.7
91.3
89
85.2
N.A.
74
77.3
N.A.
N.A.
P-Site Identity:
100
53.3
100
93.3
N.A.
86.6
86.6
N.A.
80
73.3
73.3
46.6
N.A.
33.3
46.6
N.A.
N.A.
P-Site Similarity:
100
66.6
100
100
N.A.
93.3
93.3
N.A.
86.6
86.6
80
73.3
N.A.
66.6
73.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
54.2
52
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
71.5
68.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
22
0
72
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
72
% C
% Asp:
0
0
15
0
0
72
0
0
22
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
8
0
0
0
72
8
0
0
22
15
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
15
0
8
0
0
0
0
0
36
0
% I
% Lys:
8
65
15
0
8
0
8
0
0
0
0
0
72
0
0
% K
% Leu:
0
0
0
15
0
0
0
0
8
0
79
22
0
0
0
% L
% Met:
0
0
0
65
0
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
0
0
22
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
50
0
8
0
% Q
% Arg:
0
36
8
8
0
8
79
0
0
72
0
15
8
0
0
% R
% Ser:
0
0
0
0
8
0
0
8
0
0
8
0
0
8
0
% S
% Thr:
0
0
8
8
8
0
0
8
0
8
0
0
0
22
0
% T
% Val:
0
0
0
0
0
0
8
0
0
0
8
0
0
8
29
% V
% Trp:
86
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _