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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AAAS All Species: 14.55
Human Site: S226 Identified Species: 32
UniProt: Q9NRG9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRG9 NP_056480.1 546 59574 S226 I W T L D P T S L S T R P S S
Chimpanzee Pan troglodytes XP_522403 546 59560 S226 I W T L D P T S L S T R P S S
Rhesus Macaque Macaca mulatta XP_001088225 344 37752 L48 Q W I N L P V L H L T K D P L
Dog Lupus familis XP_849797 591 64085 S271 I W T L D P T S L S T R P S S
Cat Felis silvestris
Mouse Mus musculus P58742 546 59412 S226 I W T L D P T S L S T R P S S
Rat Rattus norvegicus Q5M7T1 339 37599 I42 G G D R K I R I W G T E G D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001087073 523 57048 V226 S C V L V W H V D P T S L S T
Zebra Danio Brachydanio rerio NP_998390 499 54039 C203 G S A L A V A C Q S C L L I W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572557 466 52260 A170 I Y T K S S S A T T A T V L K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787398 472 51830 T175 A V A W K D N T I K I F I S G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191249 447 48467 E151 Q R N V K A L E W R P N G G K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 57.3 81.9 N.A. 93.5 20.5 N.A. N.A. N.A. 60.4 51.8 N.A. 28 N.A. N.A. 40.8
Protein Similarity: 100 99.8 59.8 85.2 N.A. 95.5 30.3 N.A. N.A. N.A. 72.8 66.8 N.A. 41 N.A. N.A. 54
P-Site Identity: 100 100 20 100 N.A. 100 13.3 N.A. N.A. N.A. 20 13.3 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 100 26.6 100 N.A. 100 13.3 N.A. N.A. N.A. 26.6 13.3 N.A. 40 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 24.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 19 0 10 10 10 10 0 0 10 0 0 0 0 % A
% Cys: 0 10 0 0 0 0 0 10 0 0 10 0 0 0 0 % C
% Asp: 0 0 10 0 37 10 0 0 10 0 0 0 10 10 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 19 10 0 0 0 0 0 0 0 10 0 0 19 10 10 % G
% His: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % H
% Ile: 46 0 10 0 0 10 0 10 10 0 10 0 10 10 0 % I
% Lys: 0 0 0 10 28 0 0 0 0 10 0 10 0 0 19 % K
% Leu: 0 0 0 55 10 0 10 10 37 10 0 10 19 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 10 0 0 10 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 46 0 0 0 10 10 0 37 10 0 % P
% Gln: 19 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 10 0 10 0 0 10 0 0 10 0 37 0 0 0 % R
% Ser: 10 10 0 0 10 10 10 37 0 46 0 10 0 55 46 % S
% Thr: 0 0 46 0 0 0 37 10 10 10 64 10 0 0 10 % T
% Val: 0 10 10 10 10 10 10 10 0 0 0 0 10 0 0 % V
% Trp: 0 46 0 10 0 10 0 0 19 0 0 0 0 0 10 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _