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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AAAS All Species: 13.33
Human Site: S495 Identified Species: 29.33
UniProt: Q9NRG9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRG9 NP_056480.1 546 59574 S495 N A Q F P R F S P V L G R A Q
Chimpanzee Pan troglodytes XP_522403 546 59560 S495 N A Q F P R F S P V L G R A Q
Rhesus Macaque Macaca mulatta XP_001088225 344 37752 L296 F P R F S P V L G R A Q E P P
Dog Lupus familis XP_849797 591 64085 S540 N A Q F P R F S P V L G R T Q
Cat Felis silvestris
Mouse Mus musculus P58742 546 59412 S495 N A Q F P R F S P V L G R A Q
Rat Rattus norvegicus Q5M7T1 339 37599 P290 P G S D P Q Q P T F S L T A H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001087073 523 57048 L474 G F N K G A L L S Q L W S S G
Zebra Danio Brachydanio rerio NP_998390 499 54039 A451 H P H F Q H G A L L T V C W S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572557 466 52260 Q418 F I Q K F D L Q I S A A Y Y L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787398 472 51830 E423 K E T G N T G E L I A L F N T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191249 447 48467 G399 I V S A S L V G F I R G P G E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 57.3 81.9 N.A. 93.5 20.5 N.A. N.A. N.A. 60.4 51.8 N.A. 28 N.A. N.A. 40.8
Protein Similarity: 100 99.8 59.8 85.2 N.A. 95.5 30.3 N.A. N.A. N.A. 72.8 66.8 N.A. 41 N.A. N.A. 54
P-Site Identity: 100 100 6.6 93.3 N.A. 100 13.3 N.A. N.A. N.A. 6.6 6.6 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 100 13.3 93.3 N.A. 100 20 N.A. N.A. N.A. 13.3 26.6 N.A. 6.6 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 24.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 37 0 10 0 10 0 10 0 0 28 10 0 37 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 10 0 0 0 0 10 0 10 % E
% Phe: 19 10 0 55 10 0 37 0 10 10 0 0 10 0 0 % F
% Gly: 10 10 0 10 10 0 19 10 10 0 0 46 0 10 10 % G
% His: 10 0 10 0 0 10 0 0 0 0 0 0 0 0 10 % H
% Ile: 10 10 0 0 0 0 0 0 10 19 0 0 0 0 0 % I
% Lys: 10 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 10 19 19 19 10 46 19 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 37 0 10 0 10 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 10 19 0 0 46 10 0 10 37 0 0 0 10 10 10 % P
% Gln: 0 0 46 0 10 10 10 10 0 10 0 10 0 0 37 % Q
% Arg: 0 0 10 0 0 37 0 0 0 10 10 0 37 0 0 % R
% Ser: 0 0 19 0 19 0 0 37 10 10 10 0 10 10 10 % S
% Thr: 0 0 10 0 0 10 0 0 10 0 10 0 10 10 10 % T
% Val: 0 10 0 0 0 0 19 0 0 37 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _