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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TUBG2 All Species: 56.67
Human Site: T242 Identified Species: 83.11
UniProt: Q9NRH3 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRH3 NP_057521.1 451 51092 T242 I M S A S T T T L R Y P G Y M
Chimpanzee Pan troglodytes XP_001162175 464 52570 T255 I M S A S T T T L R Y P G Y M
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548085 451 51005 T242 I M S A S T T T L R Y P G Y M
Cat Felis silvestris
Mouse Mus musculus Q8VCK3 451 51103 T242 I M S A S T T T L R Y P G Y M
Rat Rattus norvegicus P83888 451 51082 T242 I M S A S T T T L R Y P G Y M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418146 427 48240 L236 L I G L I A S L I P T P R L H
Frog Xenopus laevis P23330 451 51149 T242 I M S A S T T T L R Y P G Y M
Zebra Danio Brachydanio rerio NP_957202 451 51078 T242 I M S A S T T T L R Y P G Y M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P23257 475 53321 T242 I M S V S T T T L R Y P S Y M
Honey Bee Apis mellifera XP_394981 453 51413 T242 I M S V S T T T L R Y P S Y M
Nematode Worm Caenorhab. elegans P34475 444 49910 P244 I M S T S T A P Y R F N S A M
Sea Urchin Strong. purpuratus NP_999657 460 51977 T242 I M S T S T T T L R Y P G Y M
Poplar Tree Populus trichocarpa
Maize Zea mays Q41808 469 52822 T242 V M S A S T T T L R Y P G Y M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P38558 474 53259 T242 V M S A S T T T L R Y P G Y M
Baker's Yeast Sacchar. cerevisiae P53378 473 52609 S241 I I S S V T N S I R F P S Y M
Red Bread Mold Neurospora crassa P53377 461 51580 T242 V M S A S T T T L R Y P G Y M
Conservation
Percent
Protein Identity: 100 95 N.A. 98.2 N.A. 97.5 97.1 N.A. N.A. 90.2 96.2 96.4 N.A. 74.5 83 43.6 83.4
Protein Similarity: 100 96.5 N.A. 99.5 N.A. 98.4 98.8 N.A. N.A. 92.9 98.8 98.8 N.A. 85.4 93.1 65.1 92.6
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 6.6 100 100 N.A. 86.6 86.6 46.6 93.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 33.3 100 100 N.A. 86.6 86.6 53.3 93.3
Percent
Protein Identity: N.A. 71.4 N.A. 71.5 39.5 65.7
Protein Similarity: N.A. 82.5 N.A. 82.2 60 80.6
P-Site Identity: N.A. 93.3 N.A. 93.3 46.6 93.3
P-Site Similarity: N.A. 100 N.A. 100 80 100
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 63 0 7 7 0 0 0 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % F
% Gly: 0 0 7 0 0 0 0 0 0 0 0 0 69 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 75 13 0 0 7 0 0 0 13 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 7 0 0 7 0 0 0 7 82 0 0 0 0 7 0 % L
% Met: 0 88 0 0 0 0 0 0 0 0 0 0 0 0 94 % M
% Asn: 0 0 0 0 0 0 7 0 0 0 0 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 7 0 7 0 94 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 94 0 0 7 0 0 % R
% Ser: 0 0 94 7 88 0 7 7 0 0 0 0 25 0 0 % S
% Thr: 0 0 0 13 0 94 82 82 0 0 7 0 0 0 0 % T
% Val: 19 0 0 13 7 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 82 0 0 88 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _