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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAPOLB All Species: 40
Human Site: S188 Identified Species: 73.33
UniProt: Q9NRJ5 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRJ5 NP_064529.4 636 71681 S188 D L D L R D D S L L K N L D I
Chimpanzee Pan troglodytes XP_515496 714 80108 S187 N L D L R D D S R L R S L D I
Rhesus Macaque Macaca mulatta XP_001101831 825 90125 S189 D L D L R D D S L L K N L D I
Dog Lupus familis XP_537551 812 90509 S261 D L D L R D D S L L K N L D I
Cat Felis silvestris
Mouse Mus musculus Q9WVP6 641 72180 S188 D L D L R D D S L L K N L D I
Rat Rattus norvegicus NP_001012020 642 72321 S189 D L D L R D D S L L K N L D I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511509 736 82218 S185 D L D L R D D S L L K N L D I
Chicken Gallus gallus XP_421352 737 82879 S187 D L D L R D D S L L K N L D I
Frog Xenopus laevis P51004 715 80169 S170 D L D L R D D S L L K N L D I
Zebra Danio Brachydanio rerio NP_991321 723 80246 G187 N L D L R D D G L L K N L D I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393202 615 69546 M192 S M D L R D D M L L K N L D Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780989 670 74465 S182 N L D L T D D S L L K N L D P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29468 568 64534 K147 F V P I I K I K F S G I S I D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.2 40.8 67.7 N.A. 85 85.1 N.A. 73.7 72.8 67.8 64.3 N.A. N.A. 53.6 N.A. 50
Protein Similarity: 100 70.3 52.1 71.5 N.A. 89.6 90 N.A. 77.9 78.5 75.3 73.5 N.A. N.A. 68.8 N.A. 64.4
P-Site Identity: 100 73.3 100 100 N.A. 100 100 N.A. 100 100 100 86.6 N.A. N.A. 73.3 N.A. 80
P-Site Similarity: 100 93.3 100 100 N.A. 100 100 N.A. 100 100 100 93.3 N.A. N.A. 80 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 54.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 62 0 93 0 0 93 93 0 0 0 0 0 0 93 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 8 0 8 0 0 0 0 8 0 8 77 % I
% Lys: 0 0 0 0 0 8 0 8 0 0 85 0 0 0 0 % K
% Leu: 0 85 0 93 0 0 0 0 85 93 0 0 93 0 0 % L
% Met: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 24 0 0 0 0 0 0 0 0 0 0 85 0 0 0 % N
% Pro: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 85 0 0 0 8 0 8 0 0 0 0 % R
% Ser: 8 0 0 0 0 0 0 77 0 8 0 8 8 0 0 % S
% Thr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _