KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAPOLB
All Species:
16.67
Human Site:
S521
Identified Species:
30.56
UniProt:
Q9NRJ5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRJ5
NP_064529.4
636
71681
S521
R
L
T
D
L
N
D
S
S
F
D
L
S
A
G
Chimpanzee
Pan troglodytes
XP_515496
714
80108
S510
K
K
K
K
Q
S
L
S
D
V
N
R
S
S
G
Rhesus Macaque
Macaca mulatta
XP_001101831
825
90125
T582
R
S
S
G
N
A
A
T
S
G
N
A
A
T
K
Dog
Lupus familis
XP_537551
812
90509
L596
T
P
L
N
D
S
S
L
D
L
S
M
D
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVP6
641
72180
S521
R
L
T
A
V
T
D
S
S
L
L
L
S
I
D
Rat
Rattus norvegicus
NP_001012020
642
72321
S522
R
L
T
A
V
N
D
S
S
L
L
L
S
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511509
736
82218
L520
T
A
L
N
D
S
S
L
D
L
S
M
D
S
D
Chicken
Gallus gallus
XP_421352
737
82879
L522
T
A
L
N
D
S
S
L
D
L
S
M
D
S
D
Frog
Xenopus laevis
P51004
715
80169
S503
K
L
L
S
L
N
D
S
S
I
D
L
S
V
D
Zebra Danio
Brachydanio rerio
NP_991321
723
80246
S519
G
V
R
A
M
N
D
S
N
L
D
L
S
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393202
615
69546
L501
T
Y
V
S
P
S
L
L
K
R
E
R
K
V
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780989
670
74465
S540
S
P
P
P
V
S
E
S
P
S
K
K
V
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P29468
568
64534
K454
N
K
E
E
E
S
I
K
D
A
P
K
A
Y
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.2
40.8
67.7
N.A.
85
85.1
N.A.
73.7
72.8
67.8
64.3
N.A.
N.A.
53.6
N.A.
50
Protein Similarity:
100
70.3
52.1
71.5
N.A.
89.6
90
N.A.
77.9
78.5
75.3
73.5
N.A.
N.A.
68.8
N.A.
64.4
P-Site Identity:
100
20
13.3
0
N.A.
53.3
60
N.A.
0
0
60
40
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
46.6
40
26.6
N.A.
60
66.6
N.A.
26.6
26.6
66.6
60
N.A.
N.A.
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
24
0
8
8
0
0
8
0
8
16
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
24
0
39
0
39
0
24
0
24
0
54
% D
% Glu:
0
0
8
8
8
0
8
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
8
0
0
8
0
0
0
0
0
8
0
0
0
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
8
0
0
0
16
0
% I
% Lys:
16
16
8
8
0
0
0
8
8
0
8
16
8
0
8
% K
% Leu:
0
31
31
0
16
0
16
31
0
47
16
39
0
8
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
24
0
0
0
% M
% Asn:
8
0
0
24
8
31
0
0
8
0
16
0
0
0
0
% N
% Pro:
0
16
8
8
8
0
0
0
8
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
31
0
8
0
0
0
0
0
0
8
0
16
0
8
0
% R
% Ser:
8
8
8
16
0
54
24
54
39
8
24
0
47
31
8
% S
% Thr:
31
0
24
0
0
8
0
8
0
0
0
0
0
8
8
% T
% Val:
0
8
8
0
24
0
0
0
0
8
0
0
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _