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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAPOLB
All Species:
7.58
Human Site:
T541
Identified Species:
13.89
UniProt:
Q9NRJ5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRJ5
NP_064529.4
636
71681
T541
S
V
P
S
S
T
S
T
M
K
T
G
P
L
I
Chimpanzee
Pan troglodytes
XP_515496
714
80108
C530
R
L
S
L
D
S
S
C
L
D
S
S
R
D
T
Rhesus Macaque
Macaca mulatta
XP_001101831
825
90125
S602
V
G
V
K
R
T
S
S
P
H
K
E
E
S
P
Dog
Lupus familis
XP_537551
812
90509
K616
P
S
P
T
S
A
M
K
T
S
P
L
N
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVP6
641
72180
T541
T
A
P
S
P
T
G
T
M
K
T
G
P
L
T
Rat
Rattus norvegicus
NP_001012020
642
72321
T542
T
A
P
S
P
T
G
T
I
K
T
G
P
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511509
736
82218
K540
P
S
P
T
S
A
M
K
T
S
P
L
N
S
S
Chicken
Gallus gallus
XP_421352
737
82879
K542
P
S
P
T
S
A
M
K
T
S
P
L
N
S
S
Frog
Xenopus laevis
P51004
715
80169
A523
S
V
P
S
P
T
N
A
T
R
T
S
P
L
N
Zebra Danio
Brachydanio rerio
NP_991321
723
80246
P539
S
V
P
S
P
T
G
P
S
A
A
K
I
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393202
615
69546
G521
N
G
N
I
A
G
N
G
N
S
G
S
V
S
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780989
670
74465
E560
I
P
D
T
K
Q
G
E
D
D
S
E
V
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P29468
568
64534
N474
G
L
D
F
N
I
E
N
K
K
E
K
V
D
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.2
40.8
67.7
N.A.
85
85.1
N.A.
73.7
72.8
67.8
64.3
N.A.
N.A.
53.6
N.A.
50
Protein Similarity:
100
70.3
52.1
71.5
N.A.
89.6
90
N.A.
77.9
78.5
75.3
73.5
N.A.
N.A.
68.8
N.A.
64.4
P-Site Identity:
100
6.6
13.3
13.3
N.A.
66.6
60
N.A.
13.3
13.3
53.3
33.3
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
33.3
20
20
N.A.
73.3
73.3
N.A.
20
20
66.6
33.3
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
8
24
0
8
0
8
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
0
8
0
0
0
8
16
0
0
0
16
0
% D
% Glu:
0
0
0
0
0
0
8
8
0
0
8
16
8
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
16
0
0
0
8
31
8
0
0
8
24
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
8
0
0
8
0
0
0
8
0
16
% I
% Lys:
0
0
0
8
8
0
0
24
8
31
8
16
0
8
0
% K
% Leu:
0
16
0
8
0
0
0
0
8
0
0
24
0
31
0
% L
% Met:
0
0
0
0
0
0
24
0
16
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
8
0
16
8
8
0
0
0
24
0
8
% N
% Pro:
24
8
62
0
31
0
0
8
8
0
24
0
31
0
16
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
8
0
0
0
0
8
0
0
8
0
8
% R
% Ser:
24
24
8
39
31
8
24
8
8
31
16
24
0
39
24
% S
% Thr:
16
0
0
31
0
47
0
24
31
0
31
0
0
0
24
% T
% Val:
8
24
8
0
0
0
0
0
0
0
0
0
24
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _