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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCB10 All Species: 27.58
Human Site: Y501 Identified Species: 55.15
UniProt: Q9NRK6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRK6 NP_036221.2 738 79148 Y501 F K N V H F A Y P A R P E V P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082734 738 79029 Y501 F K N V H F A Y P A R P E V P
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9JI39 715 77170 Y466 F R N V H F T Y P A R P E V S
Rat Rattus norvegicus Q5RKI8 714 77752 Y463 F Q N V S F S Y P C R P G F N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521413 746 79754 Y443 F R G V R F A Y P T R P E V P
Chicken Gallus gallus XP_419578 623 67998 P411 L L L R L Y D P I T G T I T V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q56A55 714 77317 Y479 F M N I S F S Y P T R P G N Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569844 692 75766 F454 F Q N V F F T F P T R P E S A
Honey Bee Apis mellifera XP_625122 609 67576 T397 S L K I P S C T L V A I V G A
Nematode Worm Caenorhab. elegans P34712 1321 145045 Y1086 F K N V R F A Y P E R P E I E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WML0 644 69085 Y405 L N D V W F A Y P S R P S H M
Baker's Yeast Sacchar. cerevisiae P33310 695 75932 Y441 F K N V S F T Y P T R P K H Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 95.8 N.A. N.A. 74.1 37.2 N.A. 64.8 65.4 N.A. 37.7 N.A. 43.9 42.1 25.5 N.A.
Protein Similarity: 100 N.A. 96.8 N.A. N.A. 82.2 55.2 N.A. 75.7 75.6 N.A. 54.3 N.A. 60 59 35.8 N.A.
P-Site Identity: 100 N.A. 100 N.A. N.A. 80 53.3 N.A. 73.3 0 N.A. 46.6 N.A. 53.3 0 73.3 N.A.
P-Site Similarity: 100 N.A. 100 N.A. N.A. 86.6 66.6 N.A. 80 6.6 N.A. 60 N.A. 66.6 6.6 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 38.6 37.5 N.A.
Protein Similarity: N.A. N.A. N.A. 54.3 53.5 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 42 0 0 25 9 0 0 0 17 % A
% Cys: 0 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 9 0 0 50 0 9 % E
% Phe: 75 0 0 0 9 84 0 9 0 0 0 0 0 9 0 % F
% Gly: 0 0 9 0 0 0 0 0 0 0 9 0 17 9 0 % G
% His: 0 0 0 0 25 0 0 0 0 0 0 0 0 17 0 % H
% Ile: 0 0 0 17 0 0 0 0 9 0 0 9 9 9 0 % I
% Lys: 0 34 9 0 0 0 0 0 0 0 0 0 9 0 0 % K
% Leu: 17 17 9 0 9 0 0 0 9 0 0 0 0 0 0 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 9 67 0 0 0 0 0 0 0 0 0 0 9 9 % N
% Pro: 0 0 0 0 9 0 0 9 84 0 0 84 0 0 25 % P
% Gln: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 17 % Q
% Arg: 0 17 0 9 17 0 0 0 0 0 84 0 0 0 0 % R
% Ser: 9 0 0 0 25 9 17 0 0 9 0 0 9 9 9 % S
% Thr: 0 0 0 0 0 0 25 9 0 42 0 9 0 9 0 % T
% Val: 0 0 0 75 0 0 0 0 0 9 0 0 9 34 9 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _