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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS2
All Species:
8.18
Human Site:
S528
Identified Species:
12.86
UniProt:
Q9NRM7
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRM7
NP_055387.2
1088
120136
S528
H
L
L
L
R
S
K
S
E
Q
Y
D
L
D
S
Chimpanzee
Pan troglodytes
XP_001149147
1088
120220
S528
H
L
L
L
R
S
K
S
E
Q
Y
D
L
D
S
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
S312
A
P
G
K
A
E
P
S
L
P
A
P
N
T
V
Dog
Lupus familis
XP_534537
1097
121903
Q537
L
L
R
S
K
S
E
Q
Y
D
V
D
S
L
C
Cat
Felis silvestris
Mouse
Mus musculus
Q7TSJ6
1042
115454
E486
L
L
L
P
S
K
S
E
Q
Y
S
V
D
L
D
Rat
Rattus norvegicus
NP_001100737
1042
115346
E486
L
L
L
P
S
K
S
E
Q
Y
S
A
G
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
L555
P
P
Y
P
K
H
L
L
H
Q
N
P
S
V
P
Chicken
Gallus gallus
XP_417143
1127
126652
L567
E
Q
F
D
I
N
C
L
C
M
G
V
E
Q
T
Frog
Xenopus laevis
NP_001087838
1118
125984
L551
P
P
P
Y
P
K
H
L
L
Q
S
T
T
V
Y
Zebra Danio
Brachydanio rerio
NP_001121728
1078
119704
M506
A
S
L
E
P
V
A
M
S
G
L
Q
D
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NBK5
463
53314
Honey Bee
Apis mellifera
XP_395146
1137
124999
S601
I
G
N
N
V
N
N
S
N
N
N
S
N
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
S641
P
D
T
V
S
T
Q
S
T
S
T
Q
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
N259
P
V
Q
S
G
F
N
N
G
T
I
S
N
Y
M
Red Bread Mold
Neurospora crassa
P38679
598
67999
T101
S
P
A
Q
R
P
R
T
S
G
N
S
G
Q
Q
Conservation
Percent
Protein Identity:
100
99.4
70.5
86.6
N.A.
82.5
82.9
N.A.
48.7
75.6
47.8
63.5
N.A.
22.5
40.8
N.A.
38.6
Protein Similarity:
100
99.7
71.2
89.8
N.A.
86.5
86.9
N.A.
61
83.2
58.7
72.9
N.A.
31.4
52.7
N.A.
52
P-Site Identity:
100
100
6.6
20
N.A.
13.3
13.3
N.A.
6.6
0
6.6
13.3
N.A.
0
13.3
N.A.
13.3
P-Site Similarity:
100
100
6.6
33.3
N.A.
20
20
N.A.
13.3
13.3
6.6
13.3
N.A.
0
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.1
24.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
36.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
7
0
7
0
7
0
0
0
7
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
7
% C
% Asp:
0
7
0
7
0
0
0
0
0
7
0
20
14
14
14
% D
% Glu:
7
0
0
7
0
7
7
14
14
0
0
0
7
0
0
% E
% Phe:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
0
7
0
0
0
7
14
7
0
14
0
0
% G
% His:
14
0
0
0
0
7
7
0
7
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
0
7
14
20
14
0
0
0
0
0
0
0
0
% K
% Leu:
20
34
34
14
0
0
7
20
14
0
7
0
14
20
0
% L
% Met:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
7
% M
% Asn:
0
0
7
7
0
14
14
7
7
7
20
0
20
0
0
% N
% Pro:
27
27
7
20
14
7
7
0
0
7
0
14
0
0
7
% P
% Gln:
0
7
7
7
0
0
7
7
14
27
0
14
0
14
7
% Q
% Arg:
0
0
7
0
20
0
7
0
0
0
0
0
0
0
0
% R
% Ser:
7
7
0
14
20
20
14
34
14
7
20
20
20
14
34
% S
% Thr:
0
0
7
0
0
7
0
7
7
7
7
7
7
7
7
% T
% Val:
0
7
0
7
7
7
0
0
0
0
7
14
0
20
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
0
0
0
0
7
14
14
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _