KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AASDHPPT
All Species:
17.27
Human Site:
S258
Identified Species:
29.23
UniProt:
Q9NRN7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRN7
NP_056238.2
309
35776
S258
S
R
H
Q
D
V
P
S
Q
D
D
S
K
P
T
Chimpanzee
Pan troglodytes
XP_508734
562
63583
S511
S
R
H
Q
D
V
P
S
Q
D
D
S
K
P
T
Rhesus Macaque
Macaca mulatta
NP_001164660
309
35738
S258
S
R
H
Q
D
V
P
S
Q
D
N
S
K
P
T
Dog
Lupus familis
XP_546544
296
34079
P245
S
R
Q
Q
G
V
P
P
Q
D
D
S
K
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQF6
309
35746
Y258
S
R
H
Q
N
V
S
Y
Q
D
D
S
K
L
S
Rat
Rattus norvegicus
B2RYJ4
309
35798
Y258
S
R
H
Q
N
V
S
Y
Q
D
D
S
K
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509147
416
46338
P366
P
E
G
S
R
D
H
P
P
P
A
L
S
Q
D
Chicken
Gallus gallus
XP_417169
296
34096
D244
G
F
G
Q
Q
H
T
D
V
C
S
M
Q
P
H
Frog
Xenopus laevis
Q6DJH2
302
35017
S251
V
D
H
L
Q
H
Q
S
P
K
I
G
D
V
A
Zebra Danio
Brachydanio rerio
NP_001028901
293
33512
G242
I
S
M
S
K
K
D
G
G
S
S
C
E
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_729788
290
33154
C239
H
L
L
Q
E
D
Y
C
A
A
I
A
F
R
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_508153
297
34350
R246
C
K
E
K
K
L
P
R
E
C
V
F
R
Q
D
Sea Urchin
Strong. purpuratus
XP_786735
328
38223
G273
V
A
V
A
L
Q
L
G
P
D
R
S
S
P
C
Poplar Tree
Populus trichocarpa
XP_002315436
281
32441
R227
R
H
W
V
A
V
A
R
G
H
P
R
F
A
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.9
99.3
89
N.A.
90.9
90.6
N.A.
46.6
59.5
59.2
54.6
N.A.
31.3
N.A.
30.1
46.3
Protein Similarity:
100
54.9
100
91.5
N.A.
96.7
96.7
N.A.
59.6
74.1
73.7
69.9
N.A.
51.1
N.A.
48.8
59.4
P-Site Identity:
100
100
93.3
80
N.A.
66.6
73.3
N.A.
0
13.3
13.3
0
N.A.
6.6
N.A.
6.6
20
P-Site Similarity:
100
100
100
80
N.A.
80
86.6
N.A.
0
20
13.3
6.6
N.A.
20
N.A.
40
20
Percent
Protein Identity:
31.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
49.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
0
8
0
8
8
8
8
0
15
8
% A
% Cys:
8
0
0
0
0
0
0
8
0
15
0
8
0
0
8
% C
% Asp:
0
8
0
0
22
15
8
8
0
50
36
0
8
0
15
% D
% Glu:
0
8
8
0
8
0
0
0
8
0
0
0
8
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
8
15
0
0
% F
% Gly:
8
0
15
0
8
0
0
15
15
0
0
8
0
0
0
% G
% His:
8
8
43
0
0
15
8
0
0
8
0
0
0
0
8
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% I
% Lys:
0
8
0
8
15
8
0
0
0
8
0
0
43
0
0
% K
% Leu:
0
8
8
8
8
8
8
0
0
0
0
8
0
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
15
0
0
0
0
0
8
0
0
0
8
% N
% Pro:
8
0
0
0
0
0
36
15
22
8
8
0
0
50
8
% P
% Gln:
0
0
8
58
15
8
8
0
43
0
0
0
8
15
0
% Q
% Arg:
8
43
0
0
8
0
0
15
0
0
8
8
8
8
0
% R
% Ser:
43
8
0
15
0
0
15
29
0
8
15
50
15
0
15
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
36
% T
% Val:
15
0
8
8
0
50
0
0
8
0
8
0
0
8
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
15
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _