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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL5
All Species:
27.27
Human Site:
S119
Identified Species:
50
UniProt:
Q9NRN9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRN9
NP_054887.2
209
23719
S119
L
S
N
R
M
S
K
S
F
D
T
V
I
M
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105118
244
27775
S119
L
S
N
R
M
S
K
S
F
D
T
V
I
M
N
Dog
Lupus familis
XP_535953
209
23744
S119
L
S
N
R
M
S
K
S
F
D
T
V
I
M
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1A0
209
23644
L119
L
S
N
R
M
S
K
L
F
D
T
V
I
M
N
Rat
Rattus norvegicus
NP_001107653
209
23578
L119
L
S
S
R
M
S
K
L
F
D
T
V
I
M
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514825
209
23736
S119
L
P
D
R
M
S
K
S
F
D
T
V
I
M
N
Chicken
Gallus gallus
XP_001233695
212
23883
T119
L
P
D
S
M
S
E
T
F
D
T
V
I
M
N
Frog
Xenopus laevis
NP_001089917
198
22089
S117
P
P
D
C
L
S
K
S
V
D
T
V
I
M
N
Zebra Danio
Brachydanio rerio
NP_001005949
207
23141
K116
I
G
S
S
Y
A
K
K
F
D
T
V
I
M
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649098
213
23959
S120
I
G
S
K
W
E
K
S
F
D
T
V
L
M
N
Honey Bee
Apis mellifera
XP_392400
211
23852
Y119
L
P
G
R
F
E
K
Y
F
D
T
I
I
M
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788985
231
25949
K117
E
A
G
P
W
S
K
K
F
D
T
V
I
M
N
Poplar Tree
Populus trichocarpa
XP_002324429
213
23461
P113
R
N
L
V
W
R
G
P
I
V
D
T
V
V
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
81.9
95.2
N.A.
91.3
89.9
N.A.
89
80.6
75.5
76.5
N.A.
57.7
58.2
N.A.
59.3
Protein Similarity:
100
N.A.
82.7
98
N.A.
95.6
95.2
N.A.
95.2
91
85.6
88
N.A.
75.5
73.9
N.A.
72.2
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
86.6
N.A.
86.6
66.6
60
53.3
N.A.
53.3
60
N.A.
60
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
93.3
86.6
73.3
73.3
N.A.
80
66.6
N.A.
66.6
Percent
Protein Identity:
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
24
0
0
0
0
0
0
93
8
0
0
0
0
% D
% Glu:
8
0
0
0
0
16
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
85
0
0
0
0
0
0
% F
% Gly:
0
16
16
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
0
0
0
0
8
0
0
8
85
0
0
% I
% Lys:
0
0
0
8
0
0
85
16
0
0
0
0
0
0
0
% K
% Leu:
62
0
8
0
8
0
0
16
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
54
0
0
0
0
0
0
0
0
93
8
% M
% Asn:
0
8
31
0
0
0
0
0
0
0
0
0
0
0
93
% N
% Pro:
8
31
0
8
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
54
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
39
24
16
0
70
0
47
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
93
8
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
8
8
0
85
8
8
0
% V
% Trp:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _