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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL5
All Species:
53.33
Human Site:
S159
Identified Species:
97.78
UniProt:
Q9NRN9
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRN9
NP_054887.2
209
23719
S159
A
V
Y
S
L
H
K
S
S
T
R
E
H
V
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105118
244
27775
S159
A
V
Y
S
L
H
K
S
S
T
R
E
H
V
Q
Dog
Lupus familis
XP_535953
209
23744
S159
A
V
Y
S
L
H
K
S
S
T
R
D
H
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1A0
209
23644
S159
A
V
Y
S
L
H
K
S
S
T
R
E
H
I
Q
Rat
Rattus norvegicus
NP_001107653
209
23578
S159
A
V
Y
S
L
H
K
S
S
T
R
E
H
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514825
209
23736
S159
A
V
Y
S
L
H
K
S
S
T
R
E
H
I
Q
Chicken
Gallus gallus
XP_001233695
212
23883
T159
A
V
Y
S
L
H
K
T
S
T
R
Q
H
V
Q
Frog
Xenopus laevis
NP_001089917
198
22089
T157
S
V
Y
S
L
H
K
T
S
T
R
E
H
I
K
Zebra Danio
Brachydanio rerio
NP_001005949
207
23141
T156
A
V
Y
S
L
H
K
T
S
T
R
D
H
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649098
213
23959
T160
A
V
Y
S
L
H
K
T
S
T
R
S
Y
I
Q
Honey Bee
Apis mellifera
XP_392400
211
23852
T159
T
V
Y
S
L
H
K
T
S
T
R
N
Y
V
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788985
231
25949
T157
S
V
Y
S
L
H
K
T
S
T
R
Q
H
I
Q
Poplar Tree
Populus trichocarpa
XP_002324429
213
23461
T153
A
V
Y
S
L
H
K
T
S
T
R
E
H
V
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
81.9
95.2
N.A.
91.3
89.9
N.A.
89
80.6
75.5
76.5
N.A.
57.7
58.2
N.A.
59.3
Protein Similarity:
100
N.A.
82.7
98
N.A.
95.6
95.2
N.A.
95.2
91
85.6
88
N.A.
75.5
73.9
N.A.
72.2
P-Site Identity:
100
N.A.
100
86.6
N.A.
93.3
93.3
N.A.
93.3
86.6
73.3
80
N.A.
73.3
66.6
N.A.
73.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
93.3
80
N.A.
100
Percent
Protein Identity:
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
77
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
54
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
100
0
0
0
0
0
0
85
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
62
0
% I
% Lys:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
16
% K
% Leu:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
77
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% R
% Ser:
16
0
0
100
0
0
0
47
100
0
0
8
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
54
0
100
0
0
0
0
0
% T
% Val:
0
100
0
0
0
0
0
0
0
0
0
0
0
39
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
100
0
0
0
0
0
0
0
0
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _