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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METTL5 All Species: 53.64
Human Site: S160 Identified Species: 98.33
UniProt: Q9NRN9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRN9 NP_054887.2 209 23719 S160 V Y S L H K S S T R E H V Q K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105118 244 27775 S160 V Y S L H K S S T R E H V Q K
Dog Lupus familis XP_535953 209 23744 S160 V Y S L H K S S T R D H I Q K
Cat Felis silvestris
Mouse Mus musculus Q8K1A0 209 23644 S160 V Y S L H K S S T R E H I Q K
Rat Rattus norvegicus NP_001107653 209 23578 S160 V Y S L H K S S T R E H I Q K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514825 209 23736 S160 V Y S L H K S S T R E H I Q K
Chicken Gallus gallus XP_001233695 212 23883 S160 V Y S L H K T S T R Q H V Q K
Frog Xenopus laevis NP_001089917 198 22089 S158 V Y S L H K T S T R E H I K K
Zebra Danio Brachydanio rerio NP_001005949 207 23141 S157 V Y S L H K T S T R D H I Q K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649098 213 23959 S161 V Y S L H K T S T R S Y I Q K
Honey Bee Apis mellifera XP_392400 211 23852 S160 V Y S L H K T S T R N Y V L Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788985 231 25949 S158 V Y S L H K T S T R Q H I Q K
Poplar Tree Populus trichocarpa XP_002324429 213 23461 S154 V Y S L H K T S T R E H V K K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 81.9 95.2 N.A. 91.3 89.9 N.A. 89 80.6 75.5 76.5 N.A. 57.7 58.2 N.A. 59.3
Protein Similarity: 100 N.A. 82.7 98 N.A. 95.6 95.2 N.A. 95.2 91 85.6 88 N.A. 75.5 73.9 N.A. 72.2
P-Site Identity: 100 N.A. 100 86.6 N.A. 93.3 93.3 N.A. 93.3 86.6 80 80 N.A. 73.3 66.6 N.A. 80
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 93.3 86.6 N.A. 100
Percent
Protein Identity: 51.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 54 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 100 0 0 0 0 0 0 85 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 62 0 0 % I
% Lys: 0 0 0 0 0 100 0 0 0 0 0 0 0 16 93 % K
% Leu: 0 0 0 100 0 0 0 0 0 0 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 16 0 0 77 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % R
% Ser: 0 0 100 0 0 0 47 100 0 0 8 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 54 0 100 0 0 0 0 0 0 % T
% Val: 100 0 0 0 0 0 0 0 0 0 0 0 39 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 100 0 0 0 0 0 0 0 0 0 16 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _