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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC42SE2
All Species:
23.64
Human Site:
S27
Identified Species:
57.78
UniProt:
Q9NRR3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRR3
NP_001033791.1
84
9223
S27
R
R
R
R
I
D
R
S
M
I
G
E
P
T
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851844
84
9168
S27
R
R
R
R
I
D
R
S
M
I
G
E
P
T
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHL7
80
9058
R23
P
Q
P
K
K
K
R
R
R
I
D
R
T
M
I
Rat
Rattus norvegicus
A1L1K4
83
9077
S26
R
R
R
R
I
D
R
S
M
I
G
E
P
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKB1
78
8822
R21
E
K
P
Q
P
K
K
R
R
R
R
I
D
R
S
Frog
Xenopus laevis
Q5FVD7
84
9322
S27
R
R
R
R
I
D
R
S
M
I
G
E
P
T
N
Zebra Danio
Brachydanio rerio
A9JR56
85
9407
S27
R
R
R
R
I
D
R
S
M
I
G
E
P
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNE7
85
9567
S21
C
C
F
Q
Q
Q
R
S
P
S
R
R
P
H
Q
Honey Bee
Apis mellifera
XP_001121503
86
9643
N25
Q
Q
G
P
R
T
R
N
G
R
Q
R
S
H
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798590
92
10160
S26
R
R
R
K
I
D
R
S
M
I
G
L
P
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97.6
N.A.
41.6
98.8
N.A.
N.A.
45.2
94
92.9
N.A.
51.7
51.1
N.A.
53.2
Protein Similarity:
100
N.A.
N.A.
98.8
N.A.
63
98.8
N.A.
N.A.
59.5
96.4
95.2
N.A.
62.3
62.7
N.A.
64.1
P-Site Identity:
100
N.A.
N.A.
100
N.A.
13.3
100
N.A.
N.A.
0
100
100
N.A.
20
6.6
N.A.
86.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
26.6
100
N.A.
N.A.
26.6
100
100
N.A.
26.6
26.6
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
60
0
0
0
0
10
0
10
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
10
0
60
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% H
% Ile:
0
0
0
0
60
0
0
0
0
70
0
10
0
0
10
% I
% Lys:
0
10
0
20
10
20
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
60
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
60
% N
% Pro:
10
0
20
10
10
0
0
0
10
0
0
0
70
0
0
% P
% Gln:
10
20
0
20
10
10
0
0
0
0
10
0
0
0
20
% Q
% Arg:
60
60
60
50
10
0
90
20
20
20
20
30
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
70
0
10
0
0
10
0
10
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
10
60
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _