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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5E
All Species:
10.3
Human Site:
S166
Identified Species:
20.61
UniProt:
Q9NRR6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRR6
NP_063945.2
644
70205
S166
N
P
L
S
G
V
A
S
S
S
P
N
L
P
H
Chimpanzee
Pan troglodytes
A0FI79
644
70203
S166
N
P
L
S
G
V
A
S
S
S
P
N
L
P
H
Rhesus Macaque
Macaca mulatta
XP_001095203
644
70159
S166
N
T
L
S
G
V
A
S
S
S
P
N
L
L
H
Dog
Lupus familis
XP_849208
665
73376
G187
R
R
A
Q
D
S
A
G
G
S
P
S
S
W
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JII1
647
71896
I169
S
D
C
L
S
G
M
I
S
T
S
L
D
L
L
Rat
Rattus norvegicus
Q9WVR1
647
72220
I169
V
T
V
F
L
E
M
I
S
T
S
W
T
S
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521280
342
39128
Chicken
Gallus gallus
XP_415418
659
73992
S181
K
R
A
S
E
I
S
S
A
F
G
G
L
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648566
747
82572
P257
E
S
L
Q
N
R
S
P
I
R
P
M
A
V
S
Honey Bee
Apis mellifera
XP_392662
684
76969
G197
D
S
N
T
E
K
P
G
K
E
G
E
N
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796959
989
110275
L454
E
E
K
L
K
Q
Y
L
K
D
K
L
Q
H
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FUR2
646
73561
N195
Y
D
Q
S
P
S
C
N
N
N
A
L
H
R
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.8
71.8
N.A.
76.6
75.7
N.A.
43.9
61.1
N.A.
N.A.
N.A.
32.9
32.1
N.A.
31.3
Protein Similarity:
100
99.5
98.4
79.6
N.A.
83.6
83
N.A.
49.6
71.6
N.A.
N.A.
N.A.
46.4
48.9
N.A.
43.3
P-Site Identity:
100
100
86.6
20
N.A.
6.6
6.6
N.A.
0
20
N.A.
N.A.
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
100
86.6
26.6
N.A.
20
20
N.A.
0
40
N.A.
N.A.
N.A.
20
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
0
34
0
9
0
9
0
9
0
0
% A
% Cys:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
9
% C
% Asp:
9
17
0
0
9
0
0
0
0
9
0
0
9
0
0
% D
% Glu:
17
9
0
0
17
9
0
0
0
9
0
9
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
25
9
0
17
9
0
17
9
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
25
% H
% Ile:
0
0
0
0
0
9
0
17
9
0
0
0
0
0
9
% I
% Lys:
9
0
9
0
9
9
0
0
17
0
9
0
0
0
0
% K
% Leu:
0
0
34
17
9
0
0
9
0
0
0
25
34
25
9
% L
% Met:
0
0
0
0
0
0
17
0
0
0
0
9
0
0
0
% M
% Asn:
25
0
9
0
9
0
0
9
9
9
0
25
9
0
0
% N
% Pro:
0
17
0
0
9
0
9
9
0
0
42
0
0
17
0
% P
% Gln:
0
0
9
17
0
9
0
0
0
0
0
0
9
0
0
% Q
% Arg:
9
17
0
0
0
9
0
0
0
9
0
0
0
9
9
% R
% Ser:
9
17
0
42
9
17
17
34
42
34
17
9
9
17
25
% S
% Thr:
0
17
0
9
0
0
0
0
0
17
0
0
9
0
0
% T
% Val:
9
0
9
0
0
25
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% W
% Tyr:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _