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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC42SE1
All Species:
7.95
Human Site:
S74
Identified Species:
17.49
UniProt:
Q9NRR8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRR8
NP_001033796.1
79
8925
S74
G
N
R
D
R
P
W
S
N
S
R
G
L
_
_
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851844
84
9168
S73
Y
G
G
G
M
S
A
S
V
Q
M
Q
L
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHL7
80
9058
W74
G
N
H
R
D
R
P
W
S
N
S
R
A
L
_
Rat
Rattus norvegicus
Q5BJM7
79
8949
S74
G
N
R
D
R
P
W
S
N
S
R
A
L
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515543
18
2086
Chicken
Gallus gallus
Q5ZKB1
78
8822
Frog
Xenopus laevis
Q66KZ1
79
8910
S74
C
G
R
D
R
Q
W
S
N
S
R
V
L
_
_
Zebra Danio
Brachydanio rerio
Q6TEL3
75
8331
A68
M
R
S
K
V
P
H
A
N
G
R
N
S
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNE7
85
9567
Honey Bee
Apis mellifera
XP_001121503
86
9643
D79
M
Q
M
K
G
G
Y
D
N
A
Y
S
V
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798590
92
10160
P72
G
G
Y
E
H
L
S
P
V
A
V
D
R
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
40.4
N.A.
96.2
97.4
N.A.
21.5
83.5
83.5
68.3
N.A.
36.4
36
N.A.
33.7
Protein Similarity:
100
N.A.
N.A.
61.9
N.A.
97.5
98.7
N.A.
22.7
92.4
91.1
75.9
N.A.
50.5
55.8
N.A.
50
P-Site Identity:
100
N.A.
N.A.
13.3
N.A.
14.2
92.3
N.A.
0
0
69.2
20
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
13.3
N.A.
28.5
92.3
N.A.
0
0
69.2
26.6
N.A.
0
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
10
0
19
0
10
10
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
28
10
0
0
10
0
0
0
10
0
0
10
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
37
28
10
10
10
10
0
0
0
10
0
10
0
0
0
% G
% His:
0
0
10
0
10
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
19
0
0
0
0
0
0
0
0
0
19
10
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
0
37
19
19
% L
% Met:
19
0
10
0
10
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
28
0
0
0
0
0
0
46
10
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
28
10
10
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
10
0
0
0
10
0
10
0
0
0
% Q
% Arg:
0
10
28
10
28
10
0
0
0
0
37
10
10
0
0
% R
% Ser:
0
0
10
0
0
10
10
37
10
28
10
10
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
19
0
10
10
10
10
0
% V
% Trp:
0
0
0
0
0
0
28
10
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
0
0
0
10
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
28
37
% _