KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP22
All Species:
13.64
Human Site:
Y146
Identified Species:
37.5
UniProt:
Q9NRW4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRW4
NP_064570.1
184
20910
Y146
E
K
H
E
V
H
Q
Y
R
Q
W
L
K
E
E
Chimpanzee
Pan troglodytes
NP_001153523
179
20418
Y141
E
K
H
E
V
H
Q
Y
R
Q
W
L
K
E
E
Rhesus Macaque
Macaca mulatta
XP_001089185
184
20908
Y146
E
K
H
E
V
H
Q
Y
R
Q
W
L
R
E
E
Dog
Lupus familis
XP_848559
380
41665
F146
E
K
H
E
V
H
Q
F
R
Q
W
L
K
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99N11
184
20979
Y146
E
K
H
E
V
H
Q
Y
R
Q
W
L
R
E
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418974
206
23320
F146
E
K
H
D
V
D
Q
F
R
Q
W
L
K
E
E
Frog
Xenopus laevis
Q6GQJ8
209
23467
F146
G
K
C
E
V
H
H
F
R
T
W
L
K
D
T
Zebra Danio
Brachydanio rerio
Q566R7
183
20613
F146
Q
T
G
E
L
Q
Q
F
R
E
W
L
K
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648654
447
48720
E146
E
Q
F
K
L
S
E
E
R
R
R
L
R
E
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.2
98.3
45.7
N.A.
93.4
N.A.
N.A.
N.A.
71.8
63.1
61.4
N.A.
23.7
N.A.
N.A.
N.A.
Protein Similarity:
100
97.2
100
47.6
N.A.
100
N.A.
N.A.
N.A.
79.6
74.1
78.8
N.A.
32.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
N.A.
N.A.
N.A.
80
53.3
53.3
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
93.3
66.6
80
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
12
0
0
0
0
0
0
0
12
0
% D
% Glu:
78
0
0
78
0
0
12
12
0
12
0
0
0
89
78
% E
% Phe:
0
0
12
0
0
0
0
45
0
0
0
0
0
0
0
% F
% Gly:
12
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
67
0
0
67
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
78
0
12
0
0
0
0
0
0
0
0
67
0
0
% K
% Leu:
0
0
0
0
23
0
0
0
0
0
0
100
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
12
0
0
0
12
78
0
0
67
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
100
12
12
0
34
0
12
% R
% Ser:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
12
% T
% Val:
0
0
0
0
78
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
89
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
45
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _