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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS45
All Species:
31.82
Human Site:
S325
Identified Species:
58.33
UniProt:
Q9NRW7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRW7
NP_009190.2
570
65077
S325
Y
P
Q
F
K
K
M
S
G
T
V
S
K
H
V
Chimpanzee
Pan troglodytes
XP_001167625
570
65076
S325
Y
P
Q
F
K
K
M
S
G
T
V
S
K
H
V
Rhesus Macaque
Macaca mulatta
XP_001098282
570
65092
S325
Y
P
Q
F
K
K
M
S
G
T
V
S
K
H
V
Dog
Lupus familis
XP_533042
570
65044
S325
Y
P
Q
F
K
K
M
S
G
T
V
S
K
H
V
Cat
Felis silvestris
Mouse
Mus musculus
P97390
570
65034
S325
Y
P
Q
F
K
K
M
S
G
T
V
S
K
H
V
Rat
Rattus norvegicus
O08700
570
64875
S325
Y
P
Q
F
K
K
M
S
G
T
V
S
K
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026764
377
42830
I135
E
Q
Q
K
L
E
S
I
A
D
M
K
A
F
V
Frog
Xenopus laevis
NP_001088217
570
65179
S325
Y
P
Q
F
K
K
M
S
G
T
V
S
K
H
V
Zebra Danio
Brachydanio rerio
XP_707890
568
64880
S325
Y
P
Q
F
K
K
M
S
G
T
V
S
K
H
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24179
657
74488
N368
D
T
T
A
R
L
T
N
A
V
N
S
L
P
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792131
555
63749
F313
S
I
A
D
M
K
A
F
V
E
N
Y
P
Q
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49048
569
64924
V324
V
E
D
M
A
R
F
V
D
N
Y
P
E
Y
K
Baker's Yeast
Sacchar. cerevisiae
P38932
577
66999
P332
K
N
F
I
E
K
Y
P
E
F
R
K
L
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.4
98.9
N.A.
97
97.1
N.A.
N.A.
60.8
86.3
82.1
N.A.
23.8
N.A.
N.A.
66.6
Protein Similarity:
100
100
99.8
99.8
N.A.
99.4
99.3
N.A.
N.A.
63.8
93.5
91.7
N.A.
44.7
N.A.
N.A.
80.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
100
100
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
26.6
100
100
N.A.
20
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.6
37
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
67.1
60.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
8
0
16
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
8
0
0
0
0
8
8
0
0
0
0
0
% D
% Glu:
8
8
0
0
8
8
0
0
8
8
0
0
8
0
0
% E
% Phe:
0
0
8
62
0
0
8
8
0
8
0
0
0
8
8
% F
% Gly:
0
0
0
0
0
0
0
0
62
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
62
0
% H
% Ile:
0
8
0
8
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
8
62
77
0
0
0
0
0
16
62
0
8
% K
% Leu:
0
0
0
0
8
8
0
0
0
0
0
0
16
0
0
% L
% Met:
0
0
0
8
8
0
62
0
0
0
8
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
8
0
8
16
0
0
0
0
% N
% Pro:
0
62
0
0
0
0
0
8
0
0
0
8
8
8
0
% P
% Gln:
0
8
70
0
0
0
0
0
0
0
0
0
0
8
8
% Q
% Arg:
0
0
0
0
8
8
0
0
0
0
8
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
8
62
0
0
0
70
0
8
0
% S
% Thr:
0
8
8
0
0
0
8
0
0
62
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
8
8
8
62
0
0
0
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
62
0
0
0
0
0
8
0
0
0
8
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _