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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS45
All Species:
26.36
Human Site:
S400
Identified Species:
48.33
UniProt:
Q9NRW7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRW7
NP_009190.2
570
65077
S400
L
H
Y
E
R
H
S
S
N
S
L
P
G
L
M
Chimpanzee
Pan troglodytes
XP_001167625
570
65076
S400
L
H
Y
E
R
H
S
S
N
S
L
P
G
L
M
Rhesus Macaque
Macaca mulatta
XP_001098282
570
65092
S400
L
H
Y
E
R
H
S
S
N
S
L
P
G
L
M
Dog
Lupus familis
XP_533042
570
65044
S400
L
H
Y
E
R
H
S
S
N
S
L
P
G
L
M
Cat
Felis silvestris
Mouse
Mus musculus
P97390
570
65034
S400
L
H
Y
E
R
H
S
S
N
S
L
P
G
L
I
Rat
Rattus norvegicus
O08700
570
64875
S400
L
H
Y
E
R
H
S
S
N
S
L
P
G
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026764
377
42830
D210
N
P
K
V
T
E
L
D
A
A
R
L
V
M
L
Frog
Xenopus laevis
NP_001088217
570
65179
N400
L
H
Y
E
R
H
S
N
N
A
L
S
S
L
L
Zebra Danio
Brachydanio rerio
XP_707890
568
64880
S400
L
R
Y
E
K
H
S
S
S
I
L
P
S
L
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24179
657
74488
I443
D
K
L
R
L
Y
I
I
Y
F
I
C
A
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792131
555
63749
A388
L
D
A
C
R
L
V
A
L
Y
G
L
R
Y
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49048
569
64924
L399
D
R
L
R
L
V
M
L
Y
A
L
R
Y
E
K
Baker's Yeast
Sacchar. cerevisiae
P38932
577
66999
N407
L
A
C
I
Y
S
L
N
N
Q
T
S
S
D
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.4
98.9
N.A.
97
97.1
N.A.
N.A.
60.8
86.3
82.1
N.A.
23.8
N.A.
N.A.
66.6
Protein Similarity:
100
100
99.8
99.8
N.A.
99.4
99.3
N.A.
N.A.
63.8
93.5
91.7
N.A.
44.7
N.A.
N.A.
80.7
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
0
66.6
66.6
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
20
86.6
80
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.6
37
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
67.1
60.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
8
8
24
0
0
8
0
0
% A
% Cys:
0
0
8
8
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
16
8
0
0
0
0
0
8
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
62
0
8
0
0
0
0
0
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
47
0
0
% G
% His:
0
54
0
0
0
62
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
8
0
8
8
0
0
0
16
% I
% Lys:
0
8
8
0
8
0
0
0
0
0
0
0
0
0
16
% K
% Leu:
77
0
16
0
16
8
16
8
8
0
70
16
0
62
16
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
39
% M
% Asn:
8
0
0
0
0
0
0
16
62
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
54
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
8
% Q
% Arg:
0
16
0
16
62
0
0
0
0
0
8
8
8
0
0
% R
% Ser:
0
0
0
0
0
8
62
54
8
47
0
16
24
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% T
% Val:
0
0
0
8
0
8
8
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
62
0
8
8
0
0
16
8
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _