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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS45
All Species:
26.67
Human Site:
S542
Identified Species:
48.89
UniProt:
Q9NRW7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRW7
NP_009190.2
570
65077
S542
T
T
V
H
N
T
K
S
F
L
E
E
V
L
A
Chimpanzee
Pan troglodytes
XP_001167625
570
65076
S542
T
T
V
H
N
T
K
S
F
L
E
E
V
L
A
Rhesus Macaque
Macaca mulatta
XP_001098282
570
65092
S542
T
T
V
H
N
T
K
S
F
L
E
E
V
L
A
Dog
Lupus familis
XP_533042
570
65044
S542
T
T
V
H
N
T
K
S
F
L
E
E
V
L
A
Cat
Felis silvestris
Mouse
Mus musculus
P97390
570
65034
S542
T
T
I
H
N
T
K
S
F
L
E
E
V
L
A
Rat
Rattus norvegicus
O08700
570
64875
S542
T
T
I
H
N
T
K
S
F
L
E
E
V
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026764
377
42830
R350
L
T
V
Y
N
L
N
R
T
N
P
G
V
R
V
Frog
Xenopus laevis
NP_001088217
570
65179
S542
T
A
I
H
N
T
K
S
F
L
E
E
V
Q
A
Zebra Danio
Brachydanio rerio
XP_707890
568
64880
K541
G
T
H
I
H
N
T
K
S
F
L
E
E
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24179
657
74488
N609
G
N
Y
I
E
Y
Q
N
L
V
D
F
I
K
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792131
555
63749
R528
N
R
A
T
P
G
I
R
V
I
L
G
G
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49048
569
64924
L540
N
S
G
V
R
F
I
L
G
G
T
A
V
L
N
Baker's Yeast
Sacchar. cerevisiae
P38932
577
66999
G548
R
L
V
H
D
F
N
G
T
M
N
N
R
M
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.4
98.9
N.A.
97
97.1
N.A.
N.A.
60.8
86.3
82.1
N.A.
23.8
N.A.
N.A.
66.6
Protein Similarity:
100
100
99.8
99.8
N.A.
99.4
99.3
N.A.
N.A.
63.8
93.5
91.7
N.A.
44.7
N.A.
N.A.
80.7
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
26.6
80
13.3
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
33.3
86.6
26.6
N.A.
33.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.6
37
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
67.1
60.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
0
0
0
0
8
0
0
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
54
62
8
0
0
% E
% Phe:
0
0
0
0
0
16
0
0
54
8
0
8
0
0
0
% F
% Gly:
16
0
8
0
0
8
0
8
8
8
0
16
8
0
0
% G
% His:
0
0
8
62
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
24
16
0
0
16
0
0
8
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
54
8
0
0
0
0
0
8
0
% K
% Leu:
8
8
0
0
0
8
0
8
8
54
16
0
0
54
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
8
% M
% Asn:
16
8
0
0
62
8
16
8
0
8
8
8
0
0
8
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
8
% Q
% Arg:
8
8
0
0
8
0
0
16
0
0
0
0
8
8
8
% R
% Ser:
0
8
0
0
0
0
0
54
8
0
0
0
0
0
0
% S
% Thr:
54
62
0
8
0
54
8
0
16
0
8
0
0
8
8
% T
% Val:
0
0
47
8
0
0
0
0
8
8
0
0
70
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _