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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS45
All Species:
31.52
Human Site:
Y463
Identified Species:
57.78
UniProt:
Q9NRW7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRW7
NP_009190.2
570
65077
Y463
L
K
G
V
E
N
V
Y
T
Q
H
Q
P
F
L
Chimpanzee
Pan troglodytes
XP_001167625
570
65076
Y463
L
K
G
V
E
N
V
Y
T
Q
H
Q
P
F
L
Rhesus Macaque
Macaca mulatta
XP_001098282
570
65092
Y463
L
K
G
V
E
N
V
Y
T
Q
H
Q
P
F
L
Dog
Lupus familis
XP_533042
570
65044
Y463
L
K
G
V
E
N
V
Y
T
Q
H
Q
P
F
L
Cat
Felis silvestris
Mouse
Mus musculus
P97390
570
65034
Y463
L
K
G
V
E
N
V
Y
T
Q
H
Q
P
F
L
Rat
Rattus norvegicus
O08700
570
64875
Y463
L
K
G
V
E
N
V
Y
T
Q
H
Q
P
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026764
377
42830
V273
L
F
S
P
K
D
A
V
A
I
T
K
Q
F
L
Frog
Xenopus laevis
NP_001088217
570
65179
Y463
L
K
G
V
E
N
V
Y
T
Q
H
Q
P
F
L
Zebra Danio
Brachydanio rerio
XP_707890
568
64880
Y463
L
K
G
V
E
N
V
Y
T
Q
H
Q
P
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24179
657
74488
F506
G
T
K
T
V
S
M
F
T
K
L
V
S
Q
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792131
555
63749
F451
P
M
S
R
T
R
R
F
F
K
G
L
K
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49048
569
64924
R462
N
I
A
R
N
M
A
R
G
L
K
G
V
E
N
Baker's Yeast
Sacchar. cerevisiae
P38932
577
66999
N470
R
R
F
N
S
R
M
N
S
K
S
N
T
A
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.4
98.9
N.A.
97
97.1
N.A.
N.A.
60.8
86.3
82.1
N.A.
23.8
N.A.
N.A.
66.6
Protein Similarity:
100
100
99.8
99.8
N.A.
99.4
99.3
N.A.
N.A.
63.8
93.5
91.7
N.A.
44.7
N.A.
N.A.
80.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
20
100
93.3
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
40
100
93.3
N.A.
33.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.6
37
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
67.1
60.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
16
0
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
62
0
0
0
0
0
0
0
0
8
8
% E
% Phe:
0
8
8
0
0
0
0
16
8
0
0
0
0
62
0
% F
% Gly:
8
0
62
0
0
0
0
0
8
0
8
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
62
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
62
8
0
8
0
0
0
0
24
8
8
8
0
0
% K
% Leu:
70
0
0
0
0
0
0
0
0
8
8
8
0
8
70
% L
% Met:
0
8
0
0
0
8
16
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
8
62
0
8
0
0
0
8
0
0
8
% N
% Pro:
8
0
0
8
0
0
0
0
0
0
0
0
62
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
62
0
62
8
8
0
% Q
% Arg:
8
8
0
16
0
16
8
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
16
0
8
8
0
0
8
0
8
0
8
0
0
% S
% Thr:
0
8
0
8
8
0
0
0
70
0
8
0
8
0
0
% T
% Val:
0
0
0
62
8
0
62
8
0
0
0
8
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _