KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS45
All Species:
28.48
Human Site:
Y487
Identified Species:
52.22
UniProt:
Q9NRW7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRW7
NP_009190.2
570
65077
Y487
G
R
L
K
E
N
L
Y
P
Y
L
G
P
S
T
Chimpanzee
Pan troglodytes
XP_001167625
570
65076
Y487
G
R
L
K
E
N
L
Y
P
Y
L
G
P
S
T
Rhesus Macaque
Macaca mulatta
XP_001098282
570
65092
Y487
G
R
L
K
E
N
L
Y
P
Y
L
G
P
S
T
Dog
Lupus familis
XP_533042
570
65044
Y487
G
K
L
K
E
N
L
Y
P
Y
L
G
P
S
T
Cat
Felis silvestris
Mouse
Mus musculus
P97390
570
65034
Y487
G
R
L
K
E
N
L
Y
P
Y
L
G
P
S
T
Rat
Rattus norvegicus
O08700
570
64875
Y487
G
K
L
K
E
N
L
Y
P
Y
L
G
P
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026764
377
42830
L297
Y
T
Q
H
Q
P
L
L
Q
E
T
L
D
Q
L
Frog
Xenopus laevis
NP_001088217
570
65179
Y487
G
K
L
K
D
N
L
Y
P
Y
L
G
P
N
T
Zebra Danio
Brachydanio rerio
XP_707890
568
64880
F487
G
R
L
K
D
S
Q
F
P
Y
L
G
P
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24179
657
74488
V530
N
L
V
V
K
R
H
V
S
F
S
F
Q
I
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792131
555
63749
Q475
L
I
Y
E
T
L
D
Q
L
F
K
G
K
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49048
569
64924
T486
F
Q
T
M
E
S
I
T
R
G
R
L
R
D
V
Baker's Yeast
Sacchar. cerevisiae
P38932
577
66999
L494
I
S
S
L
L
T
D
L
S
K
N
A
L
F
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.4
98.9
N.A.
97
97.1
N.A.
N.A.
60.8
86.3
82.1
N.A.
23.8
N.A.
N.A.
66.6
Protein Similarity:
100
100
99.8
99.8
N.A.
99.4
99.3
N.A.
N.A.
63.8
93.5
91.7
N.A.
44.7
N.A.
N.A.
80.7
P-Site Identity:
100
100
100
93.3
N.A.
100
93.3
N.A.
N.A.
6.6
80
66.6
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
100
93.3
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.6
37
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
67.1
60.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
16
0
16
0
0
0
0
0
8
8
0
% D
% Glu:
0
0
0
8
54
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
8
0
16
0
8
0
8
0
% F
% Gly:
62
0
0
0
0
0
0
0
0
8
0
70
0
0
0
% G
% His:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
8
0
0
0
0
0
0
8
0
% I
% Lys:
0
24
0
62
8
0
0
0
0
8
8
0
8
0
8
% K
% Leu:
8
8
62
8
8
8
62
16
8
0
62
16
8
8
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
54
0
0
0
0
8
0
0
8
0
% N
% Pro:
0
0
0
0
0
8
0
0
62
0
0
0
62
0
0
% P
% Gln:
0
8
8
0
8
0
8
8
8
0
0
0
8
8
8
% Q
% Arg:
0
39
0
0
0
8
0
0
8
0
8
0
8
0
8
% R
% Ser:
0
8
8
0
0
16
0
0
16
0
8
0
0
54
8
% S
% Thr:
0
8
8
0
8
8
0
8
0
0
8
0
0
0
54
% T
% Val:
0
0
8
8
0
0
0
8
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
0
54
0
62
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _