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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRLF1 All Species: 15.76
Human Site: S845 Identified Species: 49.52
UniProt: Q9NRY4 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRY4 NP_004482.4 1513 172229 S845 L S Y H S S F S I R K S R L V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112719 1499 170555 S845 L S Y H S S F S I R K S R L V
Dog Lupus familis XP_850368 1503 172366 G841 L S Y H S S I G V R K D E L V
Cat Felis silvestris
Mouse Mus musculus Q91YM2 1499 170374 S845 L S Y H S S F S I R K S R L V
Rat Rattus norvegicus P81128 1513 172361 S845 L S Y H S S F S I R K S R L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510691 1429 157109 L816 S V L L D L P L G P H P K R L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VX32 1561 178754 S824 L S S Y H G T S Q Y R D E L I
Honey Bee Apis mellifera XP_624122 1551 176949 N791 I S S F H G A N A F R D E L V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.4 50.7 N.A. 96.5 94.5 N.A. 64.9 N.A. N.A. N.A. N.A. 27.9 29 N.A. N.A.
Protein Similarity: 100 N.A. 98.6 69.3 N.A. 97.6 96.3 N.A. 78.2 N.A. N.A. N.A. N.A. 49.2 48.8 N.A. N.A.
P-Site Identity: 100 N.A. 100 66.6 N.A. 100 100 N.A. 0 N.A. N.A. N.A. N.A. 26.6 20 N.A. N.A.
P-Site Similarity: 100 N.A. 100 73.3 N.A. 100 100 N.A. 13.3 N.A. N.A. N.A. N.A. 46.6 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 13 0 13 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 13 0 0 0 0 0 0 38 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 38 0 0 % E
% Phe: 0 0 0 13 0 0 50 0 0 13 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 25 0 13 13 0 0 0 0 0 0 % G
% His: 0 0 0 63 25 0 0 0 0 0 13 0 0 0 0 % H
% Ile: 13 0 0 0 0 0 13 0 50 0 0 0 0 0 13 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 63 0 13 0 0 % K
% Leu: 75 0 13 13 0 13 0 13 0 0 0 0 0 88 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 13 0 0 13 0 13 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 63 25 0 50 13 0 % R
% Ser: 13 88 25 0 63 63 0 63 0 0 0 50 0 0 0 % S
% Thr: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % T
% Val: 0 13 0 0 0 0 0 0 13 0 0 0 0 0 75 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 63 13 0 0 0 0 0 13 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _