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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RASSF1 All Species: 13.03
Human Site: T131 Identified Species: 31.85
UniProt: Q9NS23 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NS23 NP_009113.3 344 39219 T131 D E P V E W E T P D L S Q A E
Chimpanzee Pan troglodytes XP_001168270 344 39200 T131 D E P V E W E T P D L S Q A E
Rhesus Macaque Macaca mulatta XP_001100583 340 38751 T127 D E P V E W E T P D L S Q A E
Dog Lupus familis XP_850255 340 38828 I127 D E P A E W E I P D L S Q A E
Cat Felis silvestris
Mouse Mus musculus Q99MK9 340 38771 T127 D E A V E R E T P D L S Q A E
Rat Rattus norvegicus O35141 413 46661 Q198 C K A V E E T Q H P P T I Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509318 287 32765 G105 F M S L N K D G S Y T G F I K
Chicken Gallus gallus NP_001007852 256 29478 G87 N S N G I Y T G F I K V Q M E
Frog Xenopus laevis NP_001090617 273 31370 L102 T G F I K V Q L K L I R P V S
Zebra Danio Brachydanio rerio NP_001004550 363 41903 K149 Q S E V D W R K Q D L S V T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.3 92.4 N.A. 89.8 41.4 N.A. 60.4 37.7 52.3 53.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 97.9 94.4 N.A. 93.3 54.9 N.A. 68.3 50.5 64.5 66.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 86.6 20 N.A. 0 13.3 0 40 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 33.3 N.A. 20 26.6 26.6 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 10 0 0 0 0 0 0 0 0 0 50 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 50 0 0 0 10 0 10 0 0 60 0 0 0 0 0 % D
% Glu: 0 50 10 0 60 10 50 0 0 0 0 0 0 0 80 % E
% Phe: 10 0 10 0 0 0 0 0 10 0 0 0 10 0 0 % F
% Gly: 0 10 0 10 0 0 0 20 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 10 0 0 10 0 10 10 0 10 10 0 % I
% Lys: 0 10 0 0 10 10 0 10 10 0 10 0 0 0 10 % K
% Leu: 0 0 0 10 0 0 0 10 0 10 60 0 0 0 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 10 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 40 0 0 0 0 0 50 10 10 0 10 0 0 % P
% Gln: 10 0 0 0 0 0 10 10 10 0 0 0 60 10 0 % Q
% Arg: 0 0 0 0 0 10 10 0 0 0 0 10 0 0 0 % R
% Ser: 0 20 10 0 0 0 0 0 10 0 0 60 0 0 10 % S
% Thr: 10 0 0 0 0 0 20 40 0 0 10 10 0 10 0 % T
% Val: 0 0 0 60 0 10 0 0 0 0 0 10 10 10 0 % V
% Trp: 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _