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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGS18
All Species:
18.79
Human Site:
T190
Identified Species:
41.33
UniProt:
Q9NS28
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NS28
NP_570138.1
235
27582
T190
L
M
E
Q
D
S
Y
T
R
F
L
K
S
D
I
Chimpanzee
Pan troglodytes
XP_514066
235
27570
T190
L
M
E
Q
D
S
Y
T
R
F
L
K
S
D
I
Rhesus Macaque
Macaca mulatta
XP_001113061
235
27507
T190
L
M
E
Q
D
S
Y
T
R
F
L
K
S
D
I
Dog
Lupus familis
XP_849782
235
27649
T190
L
M
E
Q
D
S
Y
T
R
F
L
K
S
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q99PG4
235
27592
K190
L
M
E
H
D
S
Y
K
R
F
L
K
S
E
T
Rat
Rattus norvegicus
Q4L0E8
235
27626
K190
L
M
E
H
D
S
Y
K
R
F
L
K
S
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516413
235
27288
T190
L
M
E
Q
D
S
Y
T
R
F
L
R
S
D
I
Chicken
Gallus gallus
Q7SZC6
208
23504
S164
F
T
L
M
E
K
D
S
Y
R
R
F
L
K
S
Frog
Xenopus laevis
A1A643
201
23280
P157
V
T
K
D
L
L
E
P
T
K
A
T
F
N
G
Zebra Danio
Brachydanio rerio
Q6DGI0
174
20503
P130
N
R
L
L
E
P
T
P
H
S
L
N
E
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49808
169
19576
P125
V
N
T
N
M
G
R
P
S
A
S
T
F
D
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.3
91.4
N.A.
83.8
82.1
N.A.
70.6
39.1
34
37.4
N.A.
N.A.
N.A.
32.7
N.A.
Protein Similarity:
100
99.1
99.1
96.1
N.A.
91.9
91
N.A.
83.4
56.1
50.6
53.1
N.A.
N.A.
N.A.
49.3
N.A.
P-Site Identity:
100
100
100
100
N.A.
73.3
80
N.A.
93.3
0
0
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
80
86.6
N.A.
100
13.3
20
13.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
64
0
10
0
0
0
0
0
0
55
0
% D
% Glu:
0
0
64
0
19
0
10
0
0
0
0
0
10
19
10
% E
% Phe:
10
0
0
0
0
0
0
0
0
64
0
10
19
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
19
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
55
% I
% Lys:
0
0
10
0
0
10
0
19
0
10
0
55
0
10
0
% K
% Leu:
64
0
19
10
10
10
0
0
0
0
73
0
10
0
0
% L
% Met:
0
64
0
10
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
10
0
0
0
0
0
0
0
10
0
10
0
% N
% Pro:
0
0
0
0
0
10
0
28
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
46
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
10
0
0
0
0
10
0
64
10
10
10
0
0
0
% R
% Ser:
0
0
0
0
0
64
0
10
10
10
10
0
64
0
10
% S
% Thr:
0
19
10
0
0
0
10
46
10
0
0
19
0
0
10
% T
% Val:
19
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
64
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _