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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TOPORS
All Species:
9.09
Human Site:
S412
Identified Species:
20
UniProt:
Q9NS56
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NS56
NP_005793.2
1045
119198
S412
D
I
N
V
A
T
V
S
Q
A
P
W
D
D
E
Chimpanzee
Pan troglodytes
XP_001156839
1045
119283
S412
D
I
N
V
A
T
V
S
Q
A
P
W
D
D
E
Rhesus Macaque
Macaca mulatta
XP_001092273
1081
123033
S448
D
I
N
V
A
T
V
S
Q
A
P
W
D
D
E
Dog
Lupus familis
XP_538699
976
111922
P357
W
D
D
E
T
P
G
P
S
Y
S
S
S
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q80Z37
1033
117063
Q414
M
N
A
S
T
V
R
Q
A
P
W
D
D
E
T
Rat
Rattus norvegicus
NP_001102128
1042
117774
Q414
V
N
V
S
T
I
R
Q
A
P
W
D
D
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520205
899
102811
A280
L
H
E
F
I
S
F
A
R
S
P
F
N
I
E
Chicken
Gallus gallus
XP_424920
879
98464
K260
C
V
I
I
G
Y
V
K
P
L
A
E
R
T
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687895
999
114744
R380
V
M
P
I
A
A
V
R
H
Q
D
H
P
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394020
767
88405
V148
V
V
L
N
P
D
Q
V
A
R
R
E
Q
L
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782164
866
98741
H247
D
I
Q
S
E
E
F
H
N
H
L
R
P
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.5
87.3
N.A.
86.1
85.5
N.A.
49
30.7
N.A.
33.9
N.A.
N.A.
25.3
N.A.
25.8
Protein Similarity:
100
99.9
96.1
90.2
N.A.
91.3
90.8
N.A.
62
46.5
N.A.
50.5
N.A.
N.A.
42
N.A.
41.6
P-Site Identity:
100
100
100
0
N.A.
6.6
6.6
N.A.
13.3
6.6
N.A.
13.3
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
100
20
N.A.
13.3
13.3
N.A.
53.3
20
N.A.
26.6
N.A.
N.A.
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
37
10
0
10
28
28
10
0
0
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
37
10
10
0
0
10
0
0
0
0
10
19
46
28
0
% D
% Glu:
0
0
10
10
10
10
0
0
0
0
0
19
0
28
37
% E
% Phe:
0
0
0
10
0
0
19
0
0
0
0
10
0
10
0
% F
% Gly:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
10
10
10
0
10
0
0
0
% H
% Ile:
0
37
10
19
10
10
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
10
0
10
0
0
0
0
0
0
10
10
0
0
10
10
% L
% Met:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
28
10
0
0
0
0
10
0
0
0
10
0
10
% N
% Pro:
0
0
10
0
10
10
0
10
10
19
37
0
19
0
19
% P
% Gln:
0
0
10
0
0
0
10
19
28
10
0
0
10
0
10
% Q
% Arg:
0
0
0
0
0
0
19
10
10
10
10
10
10
0
0
% R
% Ser:
0
0
0
28
0
10
0
28
10
10
10
10
10
0
0
% S
% Thr:
0
0
0
0
28
28
0
0
0
0
0
0
0
10
19
% T
% Val:
28
19
10
28
0
10
46
10
0
0
0
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
19
28
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _