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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TOPORS
All Species:
9.09
Human Site:
S437
Identified Species:
20
UniProt:
Q9NS56
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NS56
NP_005793.2
1045
119198
S437
Q
V
H
V
T
M
S
S
L
L
N
T
S
D
S
Chimpanzee
Pan troglodytes
XP_001156839
1045
119283
S437
Q
V
H
V
T
M
S
S
L
L
N
T
S
D
S
Rhesus Macaque
Macaca mulatta
XP_001092273
1081
123033
S473
Q
V
H
V
T
M
S
S
L
L
N
T
S
D
S
Dog
Lupus familis
XP_538699
976
111922
E382
T
S
D
S
S
D
E
E
L
V
T
G
R
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q80Z37
1033
117063
L439
V
H
V
G
V
S
S
L
L
N
S
S
D
S
S
Rat
Rattus norvegicus
NP_001102128
1042
117774
L439
V
H
V
G
V
S
S
L
L
N
S
S
D
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520205
899
102811
G305
P
A
L
P
Y
E
E
G
S
Q
S
D
S
S
V
Chicken
Gallus gallus
XP_424920
879
98464
R285
E
S
I
R
E
E
K
R
E
D
V
K
K
E
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687895
999
114744
C405
S
S
S
N
D
E
D
C
V
I
I
G
Y
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394020
767
88405
P173
R
L
R
R
R
V
N
P
A
D
Y
R
R
N
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782164
866
98741
P272
F
T
S
F
A
R
S
P
H
D
M
D
T
Y
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.5
87.3
N.A.
86.1
85.5
N.A.
49
30.7
N.A.
33.9
N.A.
N.A.
25.3
N.A.
25.8
Protein Similarity:
100
99.9
96.1
90.2
N.A.
91.3
90.8
N.A.
62
46.5
N.A.
50.5
N.A.
N.A.
42
N.A.
41.6
P-Site Identity:
100
100
100
6.6
N.A.
20
20
N.A.
6.6
0
N.A.
0
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
33.3
33.3
N.A.
13.3
13.3
N.A.
13.3
N.A.
N.A.
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
0
0
10
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
10
10
0
0
28
0
19
19
28
10
% D
% Glu:
10
0
0
0
10
28
19
10
10
0
0
0
0
10
0
% E
% Phe:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
19
0
0
0
10
0
0
0
19
0
0
0
% G
% His:
0
19
28
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
10
10
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
10
10
0
10
% K
% Leu:
0
10
10
0
0
0
0
19
55
28
0
0
0
0
0
% L
% Met:
0
0
0
0
0
28
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
0
19
28
0
0
10
0
% N
% Pro:
10
0
0
10
0
0
0
19
0
0
0
0
0
0
0
% P
% Gln:
28
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% Q
% Arg:
10
0
10
19
10
10
0
10
0
0
0
10
19
0
0
% R
% Ser:
10
28
19
10
10
19
55
28
10
0
28
19
37
28
46
% S
% Thr:
10
10
0
0
28
0
0
0
0
0
10
28
10
0
10
% T
% Val:
19
28
19
28
19
10
0
0
10
10
10
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
10
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _