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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TOPORS
All Species:
16.06
Human Site:
S718
Identified Species:
35.33
UniProt:
Q9NS56
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NS56
NP_005793.2
1045
119198
S718
K
D
R
D
G
Y
E
S
S
Y
R
R
R
T
L
Chimpanzee
Pan troglodytes
XP_001156839
1045
119283
S718
K
D
R
D
G
Y
E
S
S
Y
R
R
R
T
L
Rhesus Macaque
Macaca mulatta
XP_001092273
1081
123033
S754
K
D
R
D
G
Y
E
S
S
Y
R
R
R
T
L
Dog
Lupus familis
XP_538699
976
111922
R659
Y
R
R
R
T
L
S
R
A
H
Y
S
R
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80Z37
1033
117063
Y716
R
N
K
D
R
D
G
Y
E
S
S
Y
R
R
R
Rat
Rattus norvegicus
NP_001102128
1042
117774
S719
K
D
R
D
G
Y
E
S
S
Y
R
R
R
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520205
899
102811
E582
K
R
V
F
P
S
R
E
G
R
S
R
S
R
S
Chicken
Gallus gallus
XP_424920
879
98464
G562
S
R
K
T
V
G
D
G
S
S
C
R
K
R
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687895
999
114744
S648
S
R
S
Y
S
R
T
S
P
F
N
E
R
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394020
767
88405
N450
R
E
L
T
S
S
S
N
E
S
N
S
D
S
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782164
866
98741
H549
L
H
R
S
S
S
N
H
K
P
S
H
S
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.5
87.3
N.A.
86.1
85.5
N.A.
49
30.7
N.A.
33.9
N.A.
N.A.
25.3
N.A.
25.8
Protein Similarity:
100
99.9
96.1
90.2
N.A.
91.3
90.8
N.A.
62
46.5
N.A.
50.5
N.A.
N.A.
42
N.A.
41.6
P-Site Identity:
100
100
100
13.3
N.A.
13.3
100
N.A.
13.3
13.3
N.A.
13.3
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
33.3
100
N.A.
13.3
33.3
N.A.
20
N.A.
N.A.
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
37
0
46
0
10
10
0
0
0
0
0
10
0
10
% D
% Glu:
0
10
0
0
0
0
37
10
19
0
0
10
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
37
10
10
10
10
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
10
0
10
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
46
0
19
0
0
0
0
0
10
0
0
0
10
0
0
% K
% Leu:
10
0
10
0
0
10
0
0
0
0
0
0
0
0
37
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
10
10
0
0
19
0
0
10
10
% N
% Pro:
0
0
0
0
10
0
0
0
10
10
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
19
37
55
10
10
10
10
10
0
10
37
55
64
28
19
% R
% Ser:
19
0
10
10
28
28
19
46
46
28
28
19
19
10
19
% S
% Thr:
0
0
0
19
10
0
10
0
0
0
0
0
0
37
10
% T
% Val:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
0
37
0
10
0
37
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _