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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LANCL2 All Species: 34.55
Human Site: Y259 Identified Species: 54.29
UniProt: Q9NS86 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NS86 NP_061167.1 450 50854 Y259 Y Q W H R K Q Y V G A A H G M
Chimpanzee Pan troglodytes XP_516065 399 45271 Y214 Y E W Y Q E Y Y V G A A H G L
Rhesus Macaque Macaca mulatta XP_001090911 450 50786 Y259 Y Q W H R K Q Y V G A A H G M
Dog Lupus familis XP_540359 452 51488 Y258 Y Q W H R K Q Y V G A A H G M
Cat Felis silvestris
Mouse Mus musculus Q9JJK2 450 50759 Y259 Y Q W H R K Q Y V G A A H G M
Rat Rattus norvegicus Q9QX69 399 45221 Y214 Y E W Y Q E Y Y V G A A H G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507419 502 56846 Y305 Y Q W H R K Q Y V G A A H G M
Chicken Gallus gallus XP_418874 455 51597 Y257 Y Q W H R K Q Y V G A A H G V
Frog Xenopus laevis NP_001082380 402 45423 V218 E W Y R E Y Y V G P A H G L A
Zebra Danio Brachydanio rerio Q90ZL2 405 45733 V221 E W Y Q E E Y V G A A H G L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y0Y7 419 47592 M235 G L C A I L H M L L D S P W F
Honey Bee Apis mellifera XP_624030 404 46400 Y220 Y I W H G T E Y I G G A H G L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797679 400 44476 L216 K E K S K S P L L F E W H N K
Poplar Tree Populus trichocarpa XP_002329106 417 46151 G233 W H G K R Y W G A A H G L A G
Maize Zea mays NP_001149305 401 44438 G217 W H G K K Y W G A A H G L A G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.5 98.6 82 N.A. 89.3 51.7 N.A. 68.1 80.2 50.4 50.6 N.A. 30.2 38 N.A. 46.8
Protein Similarity: 100 68 99.3 86.7 N.A. 95.7 67.5 N.A. 75.3 87.6 66 68.4 N.A. 48.4 61.5 N.A. 64.4
P-Site Identity: 100 60 100 100 N.A. 100 60 N.A. 100 93.3 6.6 6.6 N.A. 0 53.3 N.A. 6.6
P-Site Similarity: 100 93.3 100 100 N.A. 100 93.3 N.A. 100 100 13.3 20 N.A. 13.3 73.3 N.A. 26.6
Percent
Protein Identity: 36.8 39.5 N.A. N.A. N.A. N.A.
Protein Similarity: 53.3 54.8 N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 13.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 0 0 0 14 20 67 60 0 14 7 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % D
% Glu: 14 20 0 0 14 20 7 0 0 0 7 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % F
% Gly: 7 0 14 0 7 0 0 14 14 60 7 14 14 60 14 % G
% His: 0 14 0 47 0 0 7 0 0 0 14 14 67 0 0 % H
% Ile: 0 7 0 0 7 0 0 0 7 0 0 0 0 0 0 % I
% Lys: 7 0 7 14 14 40 0 0 0 0 0 0 0 0 7 % K
% Leu: 0 7 0 0 0 7 0 7 14 7 0 0 14 14 20 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 34 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % N
% Pro: 0 0 0 0 0 0 7 0 0 7 0 0 7 0 0 % P
% Gln: 0 40 0 7 14 0 40 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 7 47 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 7 0 7 0 0 0 0 0 7 0 0 7 % S
% Thr: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 14 54 0 0 0 0 0 7 % V
% Trp: 14 14 60 0 0 0 14 0 0 0 0 7 0 7 0 % W
% Tyr: 60 0 14 14 0 20 27 60 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _