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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC22A11
All Species:
9.09
Human Site:
S529
Identified Species:
22.22
UniProt:
Q9NSA0
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NSA0
NP_060954.1
550
59972
S529
D
T
I
Q
D
L
E
S
Q
K
S
T
A
A
Q
Chimpanzee
Pan troglodytes
XP_522053
550
59995
S529
D
T
I
Q
D
L
E
S
Q
K
S
T
A
A
Q
Rhesus Macaque
Macaca mulatta
XP_001084980
550
60036
S529
D
T
I
Q
D
L
E
S
Q
K
S
T
A
A
Q
Dog
Lupus familis
XP_854924
531
58434
L511
V
S
S
L
I
L
L
L
F
L
P
E
T
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFZ5
553
60176
Q533
T
I
Q
D
I
Q
K
Q
S
V
K
K
V
T
H
Rat
Rattus norvegicus
Q3ZAV1
553
60226
Q533
T
I
Q
D
I
Q
K
Q
S
V
K
K
V
T
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507099
556
61556
W533
T
I
Q
D
V
E
G
W
K
S
S
R
Q
Q
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66J52
552
61646
P525
T
I
E
E
V
E
S
P
D
K
Q
Q
K
D
V
Zebra Danio
Brachydanio rerio
Q6NYN7
560
61953
R530
T
I
Q
D
I
D
D
R
G
L
A
R
T
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95R48
567
63148
F527
T
I
A
D
G
E
R
F
G
K
K
T
K
A
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.8
70.9
N.A.
49.5
49.1
N.A.
49.2
N.A.
42.9
40.8
N.A.
30.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
97.8
83
N.A.
66.5
66
N.A.
65.4
N.A.
62.1
58.2
N.A.
48.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
0
0
N.A.
6.6
N.A.
6.6
0
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
6.6
6.6
N.A.
20
N.A.
13.3
13.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
10
0
30
40
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
30
0
0
50
30
10
10
0
10
0
0
0
0
10
10
% D
% Glu:
0
0
10
10
0
30
30
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
10
0
20
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% H
% Ile:
0
60
30
0
40
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
20
0
10
50
30
20
20
0
0
% K
% Leu:
0
0
0
10
0
40
10
10
0
20
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% P
% Gln:
0
0
40
30
0
20
0
20
30
0
10
10
10
20
30
% Q
% Arg:
0
0
0
0
0
0
10
10
0
0
0
20
0
0
10
% R
% Ser:
0
10
10
0
0
0
10
30
20
10
40
0
0
0
10
% S
% Thr:
60
30
0
0
0
0
0
0
0
0
0
40
20
20
0
% T
% Val:
10
0
0
0
20
0
0
0
0
20
0
0
20
0
10
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _