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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC22A11 All Species: 10
Human Site: S532 Identified Species: 24.44
UniProt: Q9NSA0 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NSA0 NP_060954.1 550 59972 S532 Q D L E S Q K S T A A Q G N R
Chimpanzee Pan troglodytes XP_522053 550 59995 S532 Q D L E S Q K S T A A Q G N R
Rhesus Macaque Macaca mulatta XP_001084980 550 60036 S532 Q D L E S Q K S T A A Q G N R
Dog Lupus familis XP_854924 531 58434 P514 L I L L L F L P E T Q G L P L
Cat Felis silvestris
Mouse Mus musculus Q8CFZ5 553 60176 K536 D I Q K Q S V K K V T H D T P
Rat Rattus norvegicus Q3ZAV1 553 60226 K536 D I Q K Q S V K K V T H D I A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507099 556 61556 S536 D V E G W K S S R Q Q R L Q D
Chicken Gallus gallus
Frog Xenopus laevis Q66J52 552 61646 Q528 E V E S P D K Q Q K D V N V S
Zebra Danio Brachydanio rerio Q6NYN7 560 61953 A533 D I D D R G L A R T N S K R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95R48 567 63148 K530 D G E R F G K K T K A D V Y L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 95.8 70.9 N.A. 49.5 49.1 N.A. 49.2 N.A. 42.9 40.8 N.A. 30.1 N.A. N.A. N.A.
Protein Similarity: 100 99.8 97.8 83 N.A. 66.5 66 N.A. 65.4 N.A. 62.1 58.2 N.A. 48.8 N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 0 0 N.A. 6.6 N.A. 6.6 0 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 6.6 6.6 N.A. 20 N.A. 13.3 13.3 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 30 40 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 50 30 10 10 0 10 0 0 0 0 10 10 20 0 10 % D
% Glu: 10 0 30 30 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 10 0 20 0 0 0 0 0 10 30 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 20 0 0 0 % H
% Ile: 0 40 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 20 0 10 50 30 20 20 0 0 10 0 0 % K
% Leu: 10 0 40 10 10 0 20 0 0 0 0 0 20 0 30 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 0 10 30 0 % N
% Pro: 0 0 0 0 10 0 0 10 0 0 0 0 0 10 10 % P
% Gln: 30 0 20 0 20 30 0 10 10 10 20 30 0 10 0 % Q
% Arg: 0 0 0 10 10 0 0 0 20 0 0 10 0 10 30 % R
% Ser: 0 0 0 10 30 20 10 40 0 0 0 10 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 40 20 20 0 0 10 0 % T
% Val: 0 20 0 0 0 0 20 0 0 20 0 10 10 10 0 % V
% Trp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _