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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGF21
All Species:
20.61
Human Site:
S79
Identified Species:
64.76
UniProt:
Q9NSA1
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NSA1
NP_061986.1
209
22300
S79
A
A
D
Q
S
P
E
S
L
L
Q
L
K
A
L
Chimpanzee
Pan troglodytes
XP_524333
209
22296
S79
A
A
D
Q
S
P
E
S
L
L
Q
L
K
A
L
Rhesus Macaque
Macaca mulatta
XP_001114178
204
21453
S79
A
A
H
Q
S
P
E
S
L
R
E
E
G
L
G
Dog
Lupus familis
XP_541510
209
22528
S79
A
A
R
Q
S
P
E
S
L
L
E
L
K
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJN1
210
23219
S80
A
A
H
R
S
P
E
S
L
L
E
L
K
A
L
Rat
Rattus norvegicus
Q8VI82
251
27893
D79
A
L
M
I
T
S
E
D
A
G
S
V
V
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506714
272
30387
S131
A
A
R
N
A
W
E
S
L
L
E
I
K
A
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PBT8
147
16619
T46
A
G
A
A
D
E
N
T
Y
S
I
L
R
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
84.6
84.6
N.A.
75.2
30.6
N.A.
26.8
N.A.
N.A.
24.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
88.5
88
N.A.
80.9
40.2
N.A.
42.2
N.A.
N.A.
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
53.3
86.6
N.A.
80
13.3
N.A.
53.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
60
93.3
N.A.
93.3
33.3
N.A.
80
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
100
75
13
13
13
0
0
0
13
0
0
0
0
63
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
25
0
13
0
0
13
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
13
88
0
0
0
50
13
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
0
0
0
0
0
0
13
0
0
13
0
13
% G
% His:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
13
0
0
0
0
0
0
13
13
0
25
13
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
63
0
13
% K
% Leu:
0
13
0
0
0
0
0
0
75
63
0
63
0
13
50
% L
% Met:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
13
0
0
13
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
63
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
50
0
0
0
0
0
0
25
0
0
0
0
% Q
% Arg:
0
0
25
13
0
0
0
0
0
13
0
0
13
0
0
% R
% Ser:
0
0
0
0
63
13
0
75
0
13
13
0
0
0
0
% S
% Thr:
0
0
0
0
13
0
0
13
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
13
13
0
13
% V
% Trp:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _