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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGF21
All Species:
16.36
Human Site:
Y135
Identified Species:
51.43
UniProt:
Q9NSA1
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NSA1
NP_061986.1
209
22300
Y135
L
E
D
G
Y
N
V
Y
Q
S
E
A
H
G
L
Chimpanzee
Pan troglodytes
XP_524333
209
22296
Y135
L
E
D
G
Y
N
V
Y
Q
S
E
A
H
G
L
Rhesus Macaque
Macaca mulatta
XP_001114178
204
21453
P142
H
G
L
P
L
H
L
P
G
N
K
S
P
H
R
Dog
Lupus familis
XP_541510
209
22528
Y135
L
E
D
G
Y
N
I
Y
H
S
E
T
L
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJN1
210
23219
Y136
L
E
D
G
Y
N
V
Y
Q
S
E
A
H
G
L
Rat
Rattus norvegicus
Q8VI82
251
27893
L135
L
S
P
K
H
H
Y
L
V
S
L
G
R
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506714
272
30387
Y187
R
P
D
G
Y
N
V
Y
K
S
K
K
Y
G
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PBT8
147
16619
N98
F
L
E
K
M
E
E
N
H
Y
N
T
Y
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
84.6
84.6
N.A.
75.2
30.6
N.A.
26.8
N.A.
N.A.
24.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
88.5
88
N.A.
80.9
40.2
N.A.
42.2
N.A.
N.A.
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
73.3
N.A.
100
13.3
N.A.
53.3
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
80
N.A.
100
26.6
N.A.
80
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
38
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
63
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
50
13
0
0
13
13
0
0
0
50
0
0
0
0
% E
% Phe:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
63
0
0
0
0
13
0
0
13
0
63
0
% G
% His:
13
0
0
0
13
25
0
0
25
0
0
0
38
13
0
% H
% Ile:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
25
0
0
0
0
13
0
25
13
0
0
13
% K
% Leu:
63
13
13
0
13
0
13
13
0
0
13
0
13
0
50
% L
% Met:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
63
0
13
0
13
13
0
0
0
0
% N
% Pro:
0
13
13
13
0
0
0
13
0
0
0
0
13
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
38
0
0
0
0
13
0
% Q
% Arg:
13
0
0
0
0
0
0
0
0
0
0
0
13
0
13
% R
% Ser:
0
13
0
0
0
0
0
0
0
75
0
13
0
13
13
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% T
% Val:
0
0
0
0
0
0
50
0
13
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
63
0
13
63
0
13
0
0
25
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _