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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RXFP3
All Species:
17.58
Human Site:
T421
Identified Species:
38.67
UniProt:
Q9NSD7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NSD7
NP_057652.1
469
51124
T421
S
M
R
P
F
T
A
T
T
K
P
E
H
E
D
Chimpanzee
Pan troglodytes
Q9GLN9
359
41015
P322
Q
L
L
K
Y
I
P
P
K
A
K
S
H
S
N
Rhesus Macaque
Macaca mulatta
Q9MYW9
400
44791
Q363
T
S
S
N
I
E
Q
Q
N
S
T
R
I
R
Q
Dog
Lupus familis
XP_546355
621
66853
T574
S
M
R
R
F
T
A
T
T
K
P
E
P
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGE9
472
51555
T424
N
M
R
P
F
T
A
T
T
K
P
E
P
E
D
Rat
Rattus norvegicus
P25095
359
40871
P322
Q
L
L
K
Y
I
P
P
K
A
K
S
H
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518210
464
49829
S408
S
M
R
P
F
T
A
S
T
K
P
E
P
E
E
Chicken
Gallus gallus
XP_429217
446
49201
T387
T
M
R
P
F
T
D
T
T
K
P
E
Q
E
E
Frog
Xenopus laevis
P35373
363
41522
T326
Y
I
P
P
K
M
R
T
H
A
S
V
N
T
K
Zebra Danio
Brachydanio rerio
Q7SZP9
362
40631
C325
D
L
R
F
R
S
Q
C
L
C
L
L
N
L
K
Tiger Blowfish
Takifugu rubipres
NP_001027859
408
45736
E371
T
T
K
Q
E
I
N
E
H
V
H
V
R
V
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.1
24.9
61.8
N.A.
86
24.7
N.A.
70.1
63.5
25.3
26.6
54.3
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
42.8
42.4
66.1
N.A.
90.4
42.4
N.A.
75.4
72.7
44.5
42
63.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
0
86.6
N.A.
86.6
6.6
N.A.
80
73.3
13.3
6.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
6.6
86.6
N.A.
93.3
20
N.A.
93.3
86.6
26.6
26.6
13.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
37
0
0
28
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
28
% D
% Glu:
0
0
0
0
10
10
0
10
0
0
0
46
0
46
19
% E
% Phe:
0
0
0
10
46
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
19
0
10
0
28
0
0
% H
% Ile:
0
10
0
0
10
28
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
10
19
10
0
0
0
19
46
19
0
0
0
19
% K
% Leu:
0
28
19
0
0
0
0
0
10
0
10
10
0
10
0
% L
% Met:
0
46
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
0
10
0
10
0
0
0
19
0
10
% N
% Pro:
0
0
10
46
0
0
19
19
0
0
46
0
28
0
10
% P
% Gln:
19
0
0
10
0
0
19
10
0
0
0
0
10
0
10
% Q
% Arg:
0
0
55
10
10
0
10
0
0
0
0
10
10
10
0
% R
% Ser:
28
10
10
0
0
10
0
10
0
10
10
19
0
19
10
% S
% Thr:
28
10
0
0
0
46
0
46
46
0
10
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
19
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _