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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IARS2
All Species:
16.67
Human Site:
S547
Identified Species:
45.83
UniProt:
Q9NSE4
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NSE4
NP_060530.3
1012
113792
S547
K
D
E
Y
L
I
N
S
Q
T
T
E
H
I
V
Chimpanzee
Pan troglodytes
XP_514209
1012
113771
S547
K
D
E
Y
L
I
N
S
Q
T
I
E
H
I
V
Rhesus Macaque
Macaca mulatta
XP_001099877
986
111219
R524
R
P
Y
W
C
I
S
R
Q
R
V
W
G
V
P
Dog
Lupus familis
XP_536121
964
108251
S514
K
L
V
E
Q
H
G
S
D
V
W
W
T
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIJ6
1012
112786
S547
K
D
E
Y
L
I
N
S
Q
T
T
E
H
I
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511676
1272
140999
S551
K
D
E
F
L
L
N
S
Q
T
M
E
H
V
I
Chicken
Gallus gallus
Q5ZKA2
1000
111988
S532
T
G
E
S
L
I
N
S
E
T
I
A
D
V
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001157270
983
109893
K516
T
G
E
P
L
L
N
K
H
T
V
T
H
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784868
913
104067
V464
P
I
L
T
K
E
L
V
D
H
V
T
D
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
95.1
86.7
N.A.
83.4
N.A.
N.A.
58.8
69.9
N.A.
59.7
N.A.
N.A.
N.A.
N.A.
45.4
Protein Similarity:
100
99.6
96.2
91
N.A.
91.1
N.A.
N.A.
67.5
82.6
N.A.
75.6
N.A.
N.A.
N.A.
N.A.
61.4
P-Site Identity:
100
93.3
13.3
13.3
N.A.
93.3
N.A.
N.A.
66.6
40
N.A.
40
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
40
20
N.A.
100
N.A.
N.A.
93.3
60
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
45
0
0
0
0
0
0
23
0
0
0
23
0
0
% D
% Glu:
0
0
67
12
0
12
0
0
12
0
0
45
0
0
0
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
23
0
0
0
0
12
0
0
0
0
0
12
0
0
% G
% His:
0
0
0
0
0
12
0
0
12
12
0
0
56
0
0
% H
% Ile:
0
12
0
0
0
56
0
0
0
0
23
0
0
45
34
% I
% Lys:
56
0
0
0
12
0
0
12
0
0
0
0
0
0
0
% K
% Leu:
0
12
12
0
67
23
12
0
0
0
0
0
0
23
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% N
% Pro:
12
12
0
12
0
0
0
0
0
0
0
0
0
0
23
% P
% Gln:
0
0
0
0
12
0
0
0
56
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
0
12
0
12
0
0
0
0
0
% R
% Ser:
0
0
0
12
0
0
12
67
0
0
0
0
0
0
0
% S
% Thr:
23
0
0
12
0
0
0
0
0
67
23
23
12
0
0
% T
% Val:
0
0
12
0
0
0
0
12
0
12
34
0
0
34
34
% V
% Trp:
0
0
0
12
0
0
0
0
0
0
12
23
0
0
0
% W
% Tyr:
0
0
12
34
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _