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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IARS2 All Species: 22.42
Human Site: T744 Identified Species: 61.67
UniProt: Q9NSE4 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NSE4 NP_060530.3 1012 113792 T744 V A D F N P E T D S I P V N D
Chimpanzee Pan troglodytes XP_514209 1012 113771 T744 V A D F N P E T D S I P V N D
Rhesus Macaque Macaca mulatta XP_001099877 986 111219 T718 V A D F N P E T D S I P V N D
Dog Lupus familis XP_536121 964 108251 D708 V N N M H V I D Q Y M L H L L
Cat Felis silvestris
Mouse Mus musculus Q8BIJ6 1012 112786 T744 L T G F N P E T D S V P V K N
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511676 1272 140999 T747 L A G F N P E T E S I P T E E
Chicken Gallus gallus Q5ZKA2 1000 111988 T729 M A G F N P E T D S I P P S E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001157270 983 109893 S713 L Q G F D P R S Q A V D P K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784868 913 104067 E658 L S D F K P S E G A V E T T P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 95.1 86.7 N.A. 83.4 N.A. N.A. 58.8 69.9 N.A. 59.7 N.A. N.A. N.A. N.A. 45.4
Protein Similarity: 100 99.6 96.2 91 N.A. 91.1 N.A. N.A. 67.5 82.6 N.A. 75.6 N.A. N.A. N.A. N.A. 61.4
P-Site Identity: 100 100 100 6.6 N.A. 60 N.A. N.A. 60 66.6 N.A. 13.3 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 26.6 N.A. 80 N.A. N.A. 80 86.6 N.A. 46.6 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 56 0 0 0 0 0 0 0 23 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 45 0 12 0 0 12 56 0 0 12 0 0 34 % D
% Glu: 0 0 0 0 0 0 67 12 12 0 0 12 0 12 23 % E
% Phe: 0 0 0 89 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 45 0 0 0 0 0 12 0 0 0 0 0 0 % G
% His: 0 0 0 0 12 0 0 0 0 0 0 0 12 0 0 % H
% Ile: 0 0 0 0 0 0 12 0 0 0 56 0 0 0 0 % I
% Lys: 0 0 0 0 12 0 0 0 0 0 0 0 0 23 0 % K
% Leu: 45 0 0 0 0 0 0 0 0 0 0 12 0 12 12 % L
% Met: 12 0 0 12 0 0 0 0 0 0 12 0 0 0 0 % M
% Asn: 0 12 12 0 67 0 0 0 0 0 0 0 0 34 12 % N
% Pro: 0 0 0 0 0 89 0 0 0 0 0 67 23 0 12 % P
% Gln: 0 12 0 0 0 0 0 0 23 0 0 0 0 0 12 % Q
% Arg: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % R
% Ser: 0 12 0 0 0 0 12 12 0 67 0 0 0 12 0 % S
% Thr: 0 12 0 0 0 0 0 67 0 0 0 0 23 12 0 % T
% Val: 45 0 0 0 0 12 0 0 0 0 34 0 45 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _