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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IARS2
All Species:
18.79
Human Site:
Y270
Identified Species:
51.67
UniProt:
Q9NSE4
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NSE4
NP_060530.3
1012
113792
Y270
E
H
V
S
R
S
I
Y
V
K
F
P
L
L
K
Chimpanzee
Pan troglodytes
XP_514209
1012
113771
Y270
E
H
V
S
R
S
I
Y
V
K
F
P
L
L
K
Rhesus Macaque
Macaca mulatta
XP_001099877
986
111219
A252
W
S
P
S
S
R
T
A
L
A
E
A
E
L
E
Dog
Lupus familis
XP_536121
964
108251
S242
V
S
L
I
D
G
S
S
P
V
S
F
L
V
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIJ6
1012
112786
Y270
E
H
V
S
R
S
I
Y
V
R
F
P
L
L
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511676
1272
140999
Y265
E
H
V
S
R
S
V
Y
V
R
F
P
L
L
N
Chicken
Gallus gallus
Q5ZKA2
1000
111988
Y255
Q
H
V
S
R
S
V
Y
M
K
F
P
L
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001157270
983
109893
P243
R
S
L
Y
I
T
F
P
L
L
T
L
P
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784868
913
104067
A191
Y
V
K
F
S
I
H
A
P
S
T
L
L
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
95.1
86.7
N.A.
83.4
N.A.
N.A.
58.8
69.9
N.A.
59.7
N.A.
N.A.
N.A.
N.A.
45.4
Protein Similarity:
100
99.6
96.2
91
N.A.
91.1
N.A.
N.A.
67.5
82.6
N.A.
75.6
N.A.
N.A.
N.A.
N.A.
61.4
P-Site Identity:
100
100
13.3
6.6
N.A.
86.6
N.A.
N.A.
80
80
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
26.6
20
N.A.
100
N.A.
N.A.
93.3
100
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
23
0
12
0
12
0
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
12
% D
% Glu:
45
0
0
0
0
0
0
0
0
0
12
0
12
0
12
% E
% Phe:
0
0
0
12
0
0
12
0
0
0
56
12
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% G
% His:
0
56
0
0
0
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
12
12
34
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
12
0
0
0
0
0
0
34
0
0
0
0
45
% K
% Leu:
0
0
23
0
0
0
0
0
23
12
0
23
78
67
0
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% N
% Pro:
0
0
12
0
0
0
0
12
23
0
0
56
12
0
0
% P
% Gln:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
56
12
0
0
0
23
0
0
0
0
12
% R
% Ser:
0
34
0
67
23
56
12
12
0
12
12
0
0
0
0
% S
% Thr:
0
0
0
0
0
12
12
0
0
0
23
0
0
0
0
% T
% Val:
12
12
56
0
0
0
23
0
45
12
0
0
0
12
0
% V
% Trp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% W
% Tyr:
12
0
0
12
0
0
0
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _