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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLC4
All Species:
20
Human Site:
S437
Identified Species:
40
UniProt:
Q9NSK0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NSK0
NP_612352.1
619
68640
S437
E
R
E
E
M
S
K
S
R
H
H
E
G
G
T
Chimpanzee
Pan troglodytes
XP_001135427
677
74742
S495
E
R
E
E
M
S
K
S
R
H
H
E
G
G
T
Rhesus Macaque
Macaca mulatta
XP_001092574
623
69241
S441
E
R
E
E
M
S
K
S
R
H
H
E
G
G
T
Dog
Lupus familis
XP_532144
642
71265
S460
E
R
E
E
M
S
K
S
R
H
R
D
G
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBS5
619
68594
S437
E
R
E
E
M
S
R
S
R
P
R
D
S
S
A
Rat
Rattus norvegicus
Q5PQM2
619
68945
S437
E
R
E
E
M
S
R
S
R
S
R
E
S
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508875
610
68899
M428
D
E
N
K
P
I
W
M
H
A
E
E
R
E
E
Chicken
Gallus gallus
Q5ZJ07
403
45304
R222
T
A
E
L
A
V
C
R
K
G
R
S
T
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956248
631
71269
K435
E
E
R
E
E
M
S
K
G
K
H
R
D
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46824
508
58026
K327
L
L
C
Q
N
Q
G
K
Y
D
E
V
E
K
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46822
540
60206
L359
E
K
Y
Y
K
R
A
L
E
I
Y
E
S
K
L
Sea Urchin
Strong. purpuratus
Q05090
686
76498
D445
E
E
K
G
K
F
K
D
N
A
P
Y
G
D
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.4
94.2
92.2
N.A.
94.3
95.8
N.A.
66.5
21
N.A.
73.2
N.A.
55.4
N.A.
52
57.8
Protein Similarity:
100
91.4
95.1
93.6
N.A.
96.6
97.5
N.A.
80.4
33.5
N.A.
84.4
N.A.
67.6
N.A.
67.2
70.4
P-Site Identity:
100
100
100
86.6
N.A.
53.3
73.3
N.A.
6.6
6.6
N.A.
26.6
N.A.
0
N.A.
13.3
20
P-Site Similarity:
100
100
100
93.3
N.A.
66.6
80
N.A.
20
13.3
N.A.
26.6
N.A.
6.6
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
9
0
0
17
0
0
0
0
17
% A
% Cys:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
9
0
9
0
17
9
9
0
% D
% Glu:
75
25
59
59
9
0
0
0
9
0
17
50
9
9
9
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
9
0
9
9
0
0
42
42
0
% G
% His:
0
0
0
0
0
0
0
0
9
34
34
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
9
9
9
17
0
42
17
9
9
0
0
0
17
0
% K
% Leu:
9
9
0
9
0
0
0
9
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
50
9
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
0
0
0
9
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
9
9
0
0
0
0
% P
% Gln:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
50
9
0
0
9
17
9
50
0
34
9
9
0
0
% R
% Ser:
0
0
0
0
0
50
9
50
0
9
0
9
25
17
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
50
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
9
0
0
0
0
9
0
9
9
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _