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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA3
All Species:
13.03
Human Site:
S407
Identified Species:
31.85
UniProt:
Q9NST1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NST1
NP_079501.2
481
52865
S407
C
L
L
P
A
S
R
S
Q
M
P
V
S
S
Q
Chimpanzee
Pan troglodytes
XP_515184
562
61839
S488
C
L
L
P
A
S
R
S
Q
M
P
V
S
S
Q
Rhesus Macaque
Macaca mulatta
XP_001109144
481
53057
S407
C
L
L
P
A
S
R
S
Q
M
P
V
S
G
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q91WW7
413
45753
S342
P
C
S
L
P
V
E
S
A
I
A
A
V
H
R
Rat
Rattus norvegicus
P0C548
478
52548
V402
R
A
Q
S
L
P
S
V
P
L
S
C
A
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509841
390
42660
A319
L
S
P
A
L
S
K
A
L
N
A
A
I
R
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087449
506
56166
S407
R
L
F
P
S
V
R
S
P
G
H
G
T
L
R
Zebra Danio
Brachydanio rerio
NP_001002338
473
52215
S400
G
A
A
S
E
A
N
S
G
A
P
L
R
R
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11186
621
69345
M448
S
V
L
A
S
S
T
M
E
K
E
E
H
K
E
Sea Urchin
Strong. purpuratus
XP_787685
643
72506
A496
P
E
H
M
S
A
L
A
G
Y
P
V
T
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.2
92.7
N.A.
N.A.
60
42.2
N.A.
43.8
N.A.
42
40.1
N.A.
N.A.
N.A.
28.6
30.4
Protein Similarity:
100
79.8
95
N.A.
N.A.
70.2
58.8
N.A.
57.5
N.A.
58.7
56.9
N.A.
N.A.
N.A.
45.4
47.2
P-Site Identity:
100
100
86.6
N.A.
N.A.
6.6
0
N.A.
6.6
N.A.
26.6
13.3
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
100
93.3
N.A.
N.A.
20
20
N.A.
26.6
N.A.
46.6
26.6
N.A.
N.A.
N.A.
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
10
20
30
20
0
20
10
10
20
20
10
0
0
% A
% Cys:
30
10
0
0
0
0
0
0
0
0
0
10
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
10
0
0
10
0
10
0
10
0
10
10
0
0
30
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
20
10
0
10
0
10
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
10
0
10
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
10
0
0
0
10
0
% K
% Leu:
10
40
40
10
20
0
10
0
10
10
0
10
0
10
0
% L
% Met:
0
0
0
10
0
0
0
10
0
30
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% N
% Pro:
20
0
10
40
10
10
0
0
20
0
50
0
0
10
0
% P
% Gln:
0
0
10
0
0
0
0
0
30
0
0
0
0
0
20
% Q
% Arg:
20
0
0
0
0
0
40
0
0
0
0
0
10
20
20
% R
% Ser:
10
10
10
20
30
50
10
60
0
0
10
0
30
20
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
20
10
0
% T
% Val:
0
10
0
0
0
20
0
10
0
0
0
40
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _