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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA3
All Species:
9.09
Human Site:
S70
Identified Species:
22.22
UniProt:
Q9NST1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NST1
NP_079501.2
481
52865
S70
E
Q
T
L
Q
V
L
S
D
L
V
R
K
A
R
Chimpanzee
Pan troglodytes
XP_515184
562
61839
S151
E
Q
T
L
Q
V
L
S
D
L
V
R
K
A
R
Rhesus Macaque
Macaca mulatta
XP_001109144
481
53057
S70
E
Q
T
L
Q
V
L
S
D
L
V
R
K
A
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q91WW7
413
45753
A25
L
G
F
Y
H
V
G
A
T
L
C
L
S
E
R
Rat
Rattus norvegicus
P0C548
478
52548
I70
G
E
A
G
A
N
I
I
E
V
S
K
E
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509841
390
42660
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087449
506
56166
L70
A
Q
C
C
S
D
V
L
G
V
A
K
E
A
R
Zebra Danio
Brachydanio rerio
NP_001002338
473
52215
I70
E
K
C
C
E
D
V
I
N
V
A
K
E
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11186
621
69345
L71
S
H
A
T
S
T
I
L
K
V
V
S
Q
A
R
Sea Urchin
Strong. purpuratus
XP_787685
643
72506
R68
L
K
T
A
A
K
A
R
A
R
S
L
G
P
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.2
92.7
N.A.
N.A.
60
42.2
N.A.
43.8
N.A.
42
40.1
N.A.
N.A.
N.A.
28.6
30.4
Protein Similarity:
100
79.8
95
N.A.
N.A.
70.2
58.8
N.A.
57.5
N.A.
58.7
56.9
N.A.
N.A.
N.A.
45.4
47.2
P-Site Identity:
100
100
100
N.A.
N.A.
20
13.3
N.A.
0
N.A.
20
20
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
26.6
53.3
N.A.
0
N.A.
46.6
66.6
N.A.
N.A.
N.A.
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
20
10
20
0
10
10
10
0
20
0
0
70
0
% A
% Cys:
0
0
20
20
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
20
0
0
30
0
0
0
0
0
0
% D
% Glu:
40
10
0
0
10
0
0
0
10
0
0
0
30
10
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
10
10
0
10
0
0
10
0
10
0
0
0
10
0
0
% G
% His:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
20
20
0
0
0
0
0
0
0
% I
% Lys:
0
20
0
0
0
10
0
0
10
0
0
30
30
0
0
% K
% Leu:
20
0
0
30
0
0
30
20
0
40
0
20
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
40
0
0
30
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
10
0
30
0
0
80
% R
% Ser:
10
0
0
0
20
0
0
30
0
0
20
10
10
0
0
% S
% Thr:
0
0
40
10
0
10
0
0
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
40
20
0
0
40
40
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _