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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIAPH3
All Species:
17.58
Human Site:
S271
Identified Species:
35.15
UniProt:
Q9NSV4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NSV4
NP_001035982.1
1193
136926
S271
M
S
E
E
R
S
L
S
L
L
A
K
A
V
D
Chimpanzee
Pan troglodytes
XP_509808
1253
142880
S332
M
S
E
E
R
S
L
S
L
L
A
K
A
M
D
Rhesus Macaque
Macaca mulatta
XP_001087983
1101
125595
L258
L
G
D
E
R
S
L
L
L
L
A
R
A
I
D
Dog
Lupus familis
XP_857344
981
113022
D199
A
G
E
E
R
K
I
D
R
F
S
S
I
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z207
1171
133668
S250
M
S
D
K
R
S
L
S
L
L
A
K
A
M
D
Rat
Rattus norvegicus
XP_001074393
1172
133815
S251
M
S
D
E
R
S
L
S
L
L
A
K
A
M
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512687
1111
126766
L280
L
G
D
D
R
S
L
L
L
L
A
R
A
I
D
Chicken
Gallus gallus
XP_417020
1172
133968
L243
L
G
E
E
R
S
L
L
L
L
I
K
A
I
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_683813
932
105075
Y151
C
T
L
S
S
Q
E
Y
V
H
E
L
R
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48608
1091
123153
A259
L
R
A
I
T
T
I
A
A
T
S
F
K
A
S
Honey Bee
Apis mellifera
XP_395654
1140
128906
D246
D
S
H
K
K
V
L
D
A
I
T
M
N
G
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800685
1168
130533
T313
F
A
K
L
R
A
I
T
H
I
A
S
A
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.3
54.2
73.5
N.A.
83.4
82.9
N.A.
52.2
72.5
N.A.
43.8
N.A.
36.5
37.1
N.A.
32.6
Protein Similarity:
100
93.8
71
78
N.A.
89.6
89.2
N.A.
69.3
84.1
N.A.
58.7
N.A.
56.6
60
N.A.
52.3
P-Site Identity:
100
93.3
60
26.6
N.A.
80
86.6
N.A.
53.3
66.6
N.A.
0
N.A.
0
13.3
N.A.
20
P-Site Similarity:
100
100
86.6
46.6
N.A.
100
100
N.A.
86.6
80
N.A.
13.3
N.A.
33.3
40
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
0
0
9
0
9
17
0
59
0
67
9
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
34
9
0
0
0
17
0
0
0
0
0
0
59
% D
% Glu:
0
0
34
50
0
0
9
0
0
0
9
0
0
0
17
% E
% Phe:
9
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% F
% Gly:
0
34
0
0
0
0
0
0
0
0
0
0
0
9
9
% G
% His:
0
0
9
0
0
0
0
0
9
9
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
25
0
0
17
9
0
9
25
0
% I
% Lys:
0
0
9
17
9
9
0
0
0
0
0
42
9
0
0
% K
% Leu:
34
0
9
9
0
0
67
25
59
59
0
9
0
9
0
% L
% Met:
34
0
0
0
0
0
0
0
0
0
0
9
0
25
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
75
0
0
0
9
0
0
17
9
0
0
% R
% Ser:
0
42
0
9
9
59
0
34
0
0
17
17
0
9
9
% S
% Thr:
0
9
0
0
9
9
0
9
0
9
9
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
0
9
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _