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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DIAPH3 All Species: 9.7
Human Site: S573 Identified Species: 19.39
UniProt: Q9NSV4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NSV4 NP_001035982.1 1193 136926 S573 K E G G T G H S A L P P P P P
Chimpanzee Pan troglodytes XP_509808 1253 142880 S633 G A G G T G H S A L P P P P P
Rhesus Macaque Macaca mulatta XP_001087983 1101 125595 P553 S G I P G P P P A P P L P G V
Dog Lupus familis XP_857344 981 113022 A442 E N G T G P P A L A P P L P L
Cat Felis silvestris
Mouse Mus musculus Q9Z207 1171 133668 S552 V E G E A G P S A L P P A P P
Rat Rattus norvegicus XP_001074393 1172 133815 S553 A K G E P G P S A F P P A P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512687 1111 126766 V570 G L S T S S G V S P P P P P S
Chicken Gallus gallus XP_417020 1172 133968 H550 L E A A E P H H L P P P P P P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_683813 932 105075 L394 D M G E V Y H L L S N M V K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48608 1091 123153 P524 P P G G G G A P P P P P P P M
Honey Bee Apis mellifera XP_395654 1140 128906 P521 S G S A I I A P P P P P P P P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_800685 1168 130533 L598 R Q E S E A K L S Q A N K K V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.3 54.2 73.5 N.A. 83.4 82.9 N.A. 52.2 72.5 N.A. 43.8 N.A. 36.5 37.1 N.A. 32.6
Protein Similarity: 100 93.8 71 78 N.A. 89.6 89.2 N.A. 69.3 84.1 N.A. 58.7 N.A. 56.6 60 N.A. 52.3
P-Site Identity: 100 86.6 20 26.6 N.A. 66.6 53.3 N.A. 26.6 46.6 N.A. 13.3 N.A. 46.6 33.3 N.A. 0
P-Site Similarity: 100 86.6 20 40 N.A. 66.6 60 N.A. 40 46.6 N.A. 13.3 N.A. 46.6 33.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 9 17 9 9 17 9 42 9 9 0 17 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % D
% Glu: 9 25 9 25 17 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 17 17 59 25 25 42 9 0 0 0 0 0 0 9 0 % G
% His: 0 0 0 0 0 0 34 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 9 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 9 0 0 0 0 9 0 0 0 0 0 9 17 0 % K
% Leu: 9 9 0 0 0 0 0 17 25 25 0 9 9 0 9 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 9 % M
% Asn: 0 9 0 0 0 0 0 0 0 0 9 9 0 0 0 % N
% Pro: 9 9 0 9 9 25 34 25 17 42 84 75 59 75 50 % P
% Gln: 0 9 0 0 0 0 0 0 0 9 0 0 0 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 17 0 17 9 9 9 0 34 17 9 0 0 0 0 9 % S
% Thr: 0 0 0 17 17 0 0 0 0 0 0 0 0 0 0 % T
% Val: 9 0 0 0 9 0 0 9 0 0 0 0 9 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _