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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DIAPH3 All Species: 12.12
Human Site: S624 Identified Species: 24.24
UniProt: Q9NSV4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NSV4 NP_001035982.1 1193 136926 S624 G F L G G Q N S P P L P I L P
Chimpanzee Pan troglodytes XP_509808 1253 142880 S684 G F L G G Q N S P P L P I L P
Rhesus Macaque Macaca mulatta XP_001087983 1101 125595 P593 G M I G I P P P P P P P L L F
Dog Lupus familis XP_857344 981 113022 P482 G G P V P P P P P P L G F L S
Cat Felis silvestris
Mouse Mus musculus Q9Z207 1171 133668 S604 G F L G G Q S S I P L N L P F
Rat Rattus norvegicus XP_001074393 1172 133815 F605 G F L G G Q N F I P L N L P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512687 1111 126766 L610 G P P P P P P L G G V P P P P
Chicken Gallus gallus XP_417020 1172 133968 S605 G L P G A Q W S P P S C T L P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_683813 932 105075 E434 Q Y Y K V I E E C V S Q I V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48608 1091 123153 P568 P G M G G P P P P P M P G M M
Honey Bee Apis mellifera XP_395654 1140 128906 S585 G I N S T S Q S L P L G L K P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_800685 1168 130533 L641 P P P G G S S L P H G M K E K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.3 54.2 73.5 N.A. 83.4 82.9 N.A. 52.2 72.5 N.A. 43.8 N.A. 36.5 37.1 N.A. 32.6
Protein Similarity: 100 93.8 71 78 N.A. 89.6 89.2 N.A. 69.3 84.1 N.A. 58.7 N.A. 56.6 60 N.A. 52.3
P-Site Identity: 100 100 40 33.3 N.A. 60 60 N.A. 20 53.3 N.A. 6.6 N.A. 33.3 33.3 N.A. 20
P-Site Similarity: 100 100 53.3 33.3 N.A. 73.3 66.6 N.A. 26.6 53.3 N.A. 20 N.A. 53.3 40 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 9 9 0 0 0 0 0 9 0 % E
% Phe: 0 34 0 0 0 0 0 9 0 0 0 0 9 0 25 % F
% Gly: 75 17 0 67 50 0 0 0 9 9 9 17 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 9 9 0 9 9 0 0 17 0 0 0 25 0 0 % I
% Lys: 0 0 0 9 0 0 0 0 0 0 0 0 9 9 9 % K
% Leu: 0 9 34 0 0 0 0 17 9 0 50 0 34 42 9 % L
% Met: 0 9 9 0 0 0 0 0 0 0 9 9 0 9 9 % M
% Asn: 0 0 9 0 0 0 25 0 0 0 0 17 0 0 0 % N
% Pro: 17 17 34 9 17 34 34 25 59 75 9 42 9 25 42 % P
% Gln: 9 0 0 0 0 42 9 0 0 0 0 9 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 9 0 17 17 42 0 0 17 0 0 0 9 % S
% Thr: 0 0 0 0 9 0 0 0 0 0 0 0 9 0 0 % T
% Val: 0 0 0 9 9 0 0 0 0 9 9 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _