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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIAPH3
All Species:
11.82
Human Site:
S704
Identified Species:
23.64
UniProt:
Q9NSV4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NSV4
NP_001035982.1
1193
136926
S704
E
D
I
E
E
K
K
S
I
K
K
K
I
K
E
Chimpanzee
Pan troglodytes
XP_509808
1253
142880
S764
E
D
I
E
E
K
K
S
I
K
K
K
I
K
E
Rhesus Macaque
Macaca mulatta
XP_001087983
1101
125595
P668
K
E
D
K
F
E
N
P
D
L
F
A
K
L
A
Dog
Lupus familis
XP_857344
981
113022
E552
V
D
L
L
C
K
L
E
N
T
F
C
C
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z207
1171
133668
V683
N
D
F
D
E
K
K
V
I
K
K
R
M
K
E
Rat
Rattus norvegicus
XP_001074393
1172
133815
V684
N
D
F
D
E
K
K
V
I
K
K
R
M
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512687
1111
126766
T680
L
F
S
K
L
C
L
T
F
A
T
Q
M
K
V
Chicken
Gallus gallus
XP_417020
1172
133968
S685
E
D
F
E
E
K
K
S
I
K
K
R
I
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_683813
932
105075
Q504
A
Q
A
E
L
Q
K
Q
E
E
K
I
K
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48608
1091
123153
D641
Q
E
D
K
L
A
Q
D
D
F
L
A
E
L
A
Honey Bee
Apis mellifera
XP_395654
1140
128906
S661
V
V
D
K
S
A
P
S
K
K
V
K
D
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800685
1168
130533
E720
A
D
V
D
G
K
T
E
T
K
K
K
V
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.3
54.2
73.5
N.A.
83.4
82.9
N.A.
52.2
72.5
N.A.
43.8
N.A.
36.5
37.1
N.A.
32.6
Protein Similarity:
100
93.8
71
78
N.A.
89.6
89.2
N.A.
69.3
84.1
N.A.
58.7
N.A.
56.6
60
N.A.
52.3
P-Site Identity:
100
100
0
13.3
N.A.
60
60
N.A.
6.6
86.6
N.A.
20
N.A.
0
20
N.A.
46.6
P-Site Similarity:
100
100
26.6
33.3
N.A.
80
80
N.A.
33.3
93.3
N.A.
33.3
N.A.
26.6
33.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
0
0
17
0
0
0
9
0
17
0
9
17
% A
% Cys:
0
0
0
0
9
9
0
0
0
0
0
9
9
0
0
% C
% Asp:
0
59
25
25
0
0
0
9
17
0
0
0
9
0
0
% D
% Glu:
25
17
0
34
42
9
0
17
9
9
0
0
9
0
50
% E
% Phe:
0
9
25
0
9
0
0
0
9
9
17
0
0
0
9
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
17
0
0
0
0
0
42
0
0
9
25
0
0
% I
% Lys:
9
0
0
34
0
59
50
0
9
59
59
34
17
59
9
% K
% Leu:
9
0
9
9
25
0
17
0
0
9
9
0
0
25
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% M
% Asn:
17
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% P
% Gln:
9
9
0
0
0
9
9
9
0
0
0
9
0
9
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% R
% Ser:
0
0
9
0
9
0
0
34
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
9
9
9
9
0
0
0
0
% T
% Val:
17
9
9
0
0
0
0
17
0
0
9
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _