Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DIAPH3 All Species: 19.39
Human Site: Y158 Identified Species: 38.79
UniProt: Q9NSV4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NSV4 NP_001035982.1 1193 136926 Y158 K K E M V M Q Y I N T A S K T
Chimpanzee Pan troglodytes XP_509808 1253 142880 Y219 K K E M V M Q Y I N T A S K T
Rhesus Macaque Macaca mulatta XP_001087983 1101 125595 A145 M V V Q Y I S A T A K S G G L
Dog Lupus familis XP_857344 981 113022 L99 F G R E G L G L L L D I L E R
Cat Felis silvestris
Mouse Mus musculus Q9Z207 1171 133668 Y137 K K E M V M Q Y I N T A S K T
Rat Rattus norvegicus XP_001074393 1172 133815 Y138 K K E M V M Q Y I N T A S K T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512687 1111 126766 A167 M V V Q Y I S A T A K S G G L
Chicken Gallus gallus XP_417020 1172 133968 S137 Y I S T A S K S G S L K N S R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_683813 932 105075 G51 I T S F R K Q G M K K E K P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48608 1091 123153 S144 K V Y Q C V E S L R V A L T S
Honey Bee Apis mellifera XP_395654 1140 128906 N146 S L R I A L T N N P L S W V Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_800685 1168 130533 Y200 K R D M V L Q Y M K R Q G P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.3 54.2 73.5 N.A. 83.4 82.9 N.A. 52.2 72.5 N.A. 43.8 N.A. 36.5 37.1 N.A. 32.6
Protein Similarity: 100 93.8 71 78 N.A. 89.6 89.2 N.A. 69.3 84.1 N.A. 58.7 N.A. 56.6 60 N.A. 52.3
P-Site Identity: 100 100 0 0 N.A. 100 100 N.A. 0 0 N.A. 6.6 N.A. 13.3 0 N.A. 33.3
P-Site Similarity: 100 100 13.3 20 N.A. 100 100 N.A. 13.3 20 N.A. 13.3 N.A. 40 20 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 17 0 0 17 0 17 0 42 0 0 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 0 0 34 9 0 0 9 0 0 0 0 9 0 9 0 % E
% Phe: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 9 0 9 9 9 0 0 0 25 17 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 9 0 9 0 17 0 0 34 0 0 9 0 0 0 % I
% Lys: 50 34 0 0 0 9 9 0 0 17 25 9 9 34 0 % K
% Leu: 0 9 0 0 0 25 0 9 17 9 17 0 17 0 25 % L
% Met: 17 0 0 42 0 34 0 0 17 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 9 34 0 0 9 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 9 0 0 0 17 0 % P
% Gln: 0 0 0 25 0 0 50 0 0 0 0 9 0 0 9 % Q
% Arg: 0 9 17 0 9 0 0 0 0 9 9 0 0 0 17 % R
% Ser: 9 0 17 0 0 9 17 17 0 9 0 25 34 9 17 % S
% Thr: 0 9 0 9 0 0 9 0 17 0 34 0 0 9 34 % T
% Val: 0 25 17 0 42 9 0 0 0 0 9 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 9 0 9 0 17 0 0 42 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _