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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIRT3
All Species:
25.15
Human Site:
S159
Identified Species:
55.33
UniProt:
Q9NTG7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTG7
NP_001017524.1
399
43573
S159
S
G
I
P
D
F
R
S
P
G
S
G
L
Y
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116486
345
37592
A134
D
V
A
E
L
I
R
A
R
A
C
Q
R
V
V
Dog
Lupus familis
XP_848300
330
36552
S90
S
G
I
P
D
F
R
S
P
G
S
G
L
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R104
257
28804
G60
L
A
K
E
L
Y
P
G
H
Y
R
P
N
V
T
Rat
Rattus norvegicus
Q5RJQ4
350
39301
E92
S
Y
F
K
K
H
P
E
P
F
F
A
L
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420920
346
38618
S106
S
G
I
P
D
F
R
S
P
G
S
G
L
Y
S
Frog
Xenopus laevis
NP_001089567
350
39249
S111
S
G
I
P
D
F
R
S
P
G
S
G
I
Y
D
Zebra Danio
Brachydanio rerio
Q7ZVK3
379
42296
S96
A
G
I
P
D
F
R
S
P
G
T
G
L
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650880
355
40094
Y94
T
A
I
F
D
L
D
Y
F
E
K
N
P
A
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21921
607
68747
S167
C
G
I
P
D
F
R
S
K
D
G
I
Y
A
R
Sea Urchin
Strong. purpuratus
XP_001186397
463
51241
S146
S
G
I
P
D
F
R
S
P
G
S
G
L
Y
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
77.9
67.4
N.A.
55.1
40.8
N.A.
N.A.
62.4
45.6
42.6
N.A.
42.8
N.A.
23.5
41.6
Protein Similarity:
100
N.A.
80.1
73.9
N.A.
58.9
55.1
N.A.
N.A.
70.6
60.1
60.6
N.A.
57.8
N.A.
37.4
54.2
P-Site Identity:
100
N.A.
6.6
100
N.A.
0
20
N.A.
N.A.
100
86.6
80
N.A.
13.3
N.A.
46.6
93.3
P-Site Similarity:
100
N.A.
13.3
100
N.A.
13.3
20
N.A.
N.A.
100
93.3
100
N.A.
20
N.A.
46.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
10
0
0
0
0
10
0
10
0
10
0
28
10
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
0
0
0
73
0
10
0
0
10
0
0
0
0
19
% D
% Glu:
0
0
0
19
0
0
0
10
0
10
0
0
0
0
0
% E
% Phe:
0
0
10
10
0
64
0
0
10
10
10
0
0
0
0
% F
% Gly:
0
64
0
0
0
0
0
10
0
55
10
55
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
73
0
0
10
0
0
0
0
0
10
10
0
0
% I
% Lys:
0
0
10
10
10
0
0
0
10
0
10
0
0
0
10
% K
% Leu:
10
0
0
0
19
10
0
0
0
0
0
0
55
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% N
% Pro:
0
0
0
64
0
0
19
0
64
0
0
10
10
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
73
0
10
0
10
0
10
0
10
% R
% Ser:
55
0
0
0
0
0
0
64
0
0
46
0
0
0
28
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
19
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
10
0
10
0
10
0
0
10
55
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _