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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP8A2 All Species: 28.48
Human Site: T1141 Identified Species: 52.22
UniProt: Q9NTI2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NTI2 NP_057613.4 1148 129242 T1141 V I R A Y D T T K K K S R K K
Chimpanzee Pan troglodytes XP_522636 1304 144347 T1297 V I R A Y D T T K K K S R K K
Rhesus Macaque Macaca mulatta XP_001092901 1188 133474 T1181 V I R A Y D T T K K K C R K K
Dog Lupus familis XP_543162 1175 133105 S1159 C S Y D T T K S Q G C K S L N
Cat Felis silvestris
Mouse Mus musculus P98200 1148 129398 T1141 I V R A Y D T T K E N S R K K
Rat Rattus norvegicus XP_223390 1134 128100 T1127 V I R A Y D T T K Q R P D E W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518853 932 104820 T925 V I R A Y D T T K Q R A D E W
Chicken Gallus gallus XP_417130 1170 131762 T1163 V V R S Y D T T K R R T E I E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002666697 916 102033
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137649 1324 149578
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200260 1167 132097 T1152 V I R A Y D T T K R P T G A V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9XIE6 1213 137734 A1202 A W D V A R R A S M R S R P K
Baker's Yeast Sacchar. cerevisiae P39524 1355 153826 N1313 D A S A N P F N D N N G L G S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88 95 67.2 N.A. 94.6 65.6 N.A. 54 82 N.A. 58.8 N.A. 49.2 N.A. N.A. 56.7
Protein Similarity: 100 88 95.4 78.8 N.A. 97.2 79 N.A. 66.1 89.9 N.A. 65.7 N.A. 63.5 N.A. N.A. 74.5
P-Site Identity: 100 100 93.3 0 N.A. 73.3 60 N.A. 60 46.6 N.A. 0 N.A. 0 N.A. N.A. 60
P-Site Similarity: 100 100 93.3 13.3 N.A. 93.3 80 N.A. 86.6 86.6 N.A. 0 N.A. 0 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. 40.7 38.6 N.A.
Protein Similarity: N.A. N.A. N.A. 58.5 55.5 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 62 8 0 0 8 0 0 0 8 0 8 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % C
% Asp: 8 0 8 8 0 62 0 0 8 0 0 0 16 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 8 0 0 8 16 8 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 0 8 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 47 0 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 0 8 0 62 24 24 8 0 31 39 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 8 0 8 16 0 0 0 8 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 8 8 0 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 16 0 0 0 0 0 % Q
% Arg: 0 0 62 0 0 8 8 0 0 16 31 0 39 0 0 % R
% Ser: 0 8 8 8 0 0 0 8 8 0 0 31 8 0 8 % S
% Thr: 0 0 0 0 8 8 62 62 0 0 0 16 0 0 0 % T
% Val: 54 16 0 8 0 0 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 16 % W
% Tyr: 0 0 8 0 62 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _