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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP8A2 All Species: 26.67
Human Site: Y208 Identified Species: 48.89
UniProt: Q9NTI2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NTI2 NP_057613.4 1148 129242 Y208 E G P N R H L Y D F T G N L N
Chimpanzee Pan troglodytes XP_522636 1304 144347 Y364 E G P N R H L Y D F T G N L N
Rhesus Macaque Macaca mulatta XP_001092901 1188 133474 Y248 E G P N R H L Y D F T G N L N
Dog Lupus familis XP_543162 1175 133105 N230 E G P N R H F N T F I G T L Y
Cat Felis silvestris
Mouse Mus musculus P98200 1148 129398 Y208 E G P N R H L Y D F T G N L H
Rat Rattus norvegicus XP_223390 1134 128100 I206 G L P A T S D I K D I D S L M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518853 932 104820 L10 P L G A D Q L L L R G A Q L R
Chicken Gallus gallus XP_417130 1170 131762 Y230 E G P N R H L Y D F T G T L R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002666697 916 102033
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137649 1324 149578 A347 G I N T F F P A D L I L L S S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200260 1167 132097 Y224 E L P N R H L Y E F V G N M K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9XIE6 1213 137734 Y230 E Q P N N S L Y T F T G N L V
Baker's Yeast Sacchar. cerevisiae P39524 1355 153826 Y380 E Q P N S S L Y T Y E G T M T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88 95 67.2 N.A. 94.6 65.6 N.A. 54 82 N.A. 58.8 N.A. 49.2 N.A. N.A. 56.7
Protein Similarity: 100 88 95.4 78.8 N.A. 97.2 79 N.A. 66.1 89.9 N.A. 65.7 N.A. 63.5 N.A. N.A. 74.5
P-Site Identity: 100 100 100 60 N.A. 93.3 13.3 N.A. 13.3 86.6 N.A. 0 N.A. 6.6 N.A. N.A. 66.6
P-Site Similarity: 100 100 100 60 N.A. 100 20 N.A. 13.3 86.6 N.A. 0 N.A. 13.3 N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 40.7 38.6 N.A.
Protein Similarity: N.A. N.A. N.A. 58.5 55.5 N.A.
P-Site Identity: N.A. N.A. N.A. 66.6 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 0 0 0 8 0 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 8 0 47 8 0 8 0 0 0 % D
% Glu: 70 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 8 8 8 0 0 62 0 0 0 0 0 % F
% Gly: 16 47 8 0 0 0 0 0 0 0 8 70 0 0 0 % G
% His: 0 0 0 0 0 54 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 8 0 0 0 0 0 8 0 0 24 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % K
% Leu: 0 24 0 0 0 0 70 8 8 8 0 8 8 70 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 8 % M
% Asn: 0 0 8 70 8 0 0 8 0 0 0 0 47 0 24 % N
% Pro: 8 0 77 0 0 0 8 0 0 0 0 0 0 0 0 % P
% Gln: 0 16 0 0 0 8 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 0 0 54 0 0 0 0 8 0 0 0 0 16 % R
% Ser: 0 0 0 0 8 24 0 0 0 0 0 0 8 8 8 % S
% Thr: 0 0 0 8 8 0 0 0 24 0 47 0 24 0 8 % T
% Val: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 62 0 8 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _