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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDS5B All Species: 27.27
Human Site: S1161 Identified Species: 50
UniProt: Q9NTI5 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NTI5 NP_055847.1 1447 164667 S1161 T V S N A S S S S N P S S P G
Chimpanzee Pan troglodytes XP_509623 1487 169149 S1201 T V S N A S S S S N P S S P G
Rhesus Macaque Macaca mulatta XP_001118201 1528 173307 S1241 T V S N A S S S S N P S S P G
Dog Lupus familis XP_543139 1623 183240 S1336 T V S N A S S S S N P S S P G
Cat Felis silvestris
Mouse Mus musculus Q4VA53 1446 164401 S1161 T V S N A S S S S N P S S P G
Rat Rattus norvegicus Q6TRW4 1447 164441 S1161 T V S N A S S S S N P S S P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509617 1452 165101 S1161 T V S N A S S S S N P S S P G
Chicken Gallus gallus Q5F3U9 1412 161007 A1133 K A A N V L G A V N K P L S S
Frog Xenopus laevis Q5U241 1464 166906 G1161 T V S N A S S G S N P S S P G
Zebra Danio Brachydanio rerio A1L1F4 1320 148940 K1047 N S H S F L R K M V E N I K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610719 1218 138870 L945 R E I F A R K L H K G L S R S
Honey Bee Apis mellifera XP_623860 1203 137941 C930 G R G I P N K C L P L D F M G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790621 1624 181368 A1153 V V N E S G D A S I V T N G N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 94.3 88.4 N.A. 96.3 96.4 N.A. 94.4 91.4 84.4 63.9 N.A. 27.9 33.6 N.A. 40.3
Protein Similarity: 100 97.1 94.5 88.8 N.A. 97.7 97.7 N.A. 96.6 94.6 90.4 75.4 N.A. 46.5 52.3 N.A. 58.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 13.3 93.3 0 N.A. 13.3 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 26.6 93.3 13.3 N.A. 13.3 13.3 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 70 0 0 16 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % D
% Glu: 0 8 0 8 0 0 0 0 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 8 8 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 8 0 8 0 0 8 8 8 0 0 8 0 0 8 70 % G
% His: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 8 8 0 0 0 0 0 8 0 0 8 0 0 % I
% Lys: 8 0 0 0 0 0 16 8 0 8 8 0 0 8 0 % K
% Leu: 0 0 0 0 0 16 0 8 8 0 8 8 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % M
% Asn: 8 0 8 70 0 8 0 0 0 70 0 8 8 0 8 % N
% Pro: 0 0 0 0 8 0 0 0 0 8 62 8 0 62 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 8 8 0 0 0 8 8 0 0 0 0 0 0 8 0 % R
% Ser: 0 8 62 8 8 62 62 54 70 0 0 62 70 8 16 % S
% Thr: 62 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % T
% Val: 8 70 0 0 8 0 0 0 8 8 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _